EMT and EndMT: emerging roles in age-related macular degeneration
DY Shu, E Butcher, M Saint-Geniez - International journal of molecular …, 2020 - mdpi.com
Epithelial–mesenchymal transition (EMT) and endothelial–mesenchymal transition (EndMT)
are physiological processes required for normal embryogenesis. However, these processes …
are physiological processes required for normal embryogenesis. However, these processes …
Interactions of the choroid, Bruch's membrane, retinal pigment epithelium, and neurosensory retina collaborate to form the outer blood-retinal-barrier
MA Fields, LV Del Priore, RA Adelman… - Progress in retinal and …, 2020 - Elsevier
The three interacting components of the outer blood-retinal barrier are the retinal pigment
epithelium (RPE), choriocapillaris, and Bruch's membrane, the extracellular matrix that lies …
epithelium (RPE), choriocapillaris, and Bruch's membrane, the extracellular matrix that lies …
Stem cell based therapies for age-related macular degeneration: the promises and the challenges
Age-related macular degeneration (AMD) is the leading cause of blindness among the
elderly in developed countries. AMD is classified as either neovascular (NV-AMD) or non …
elderly in developed countries. AMD is classified as either neovascular (NV-AMD) or non …
Aging, age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins
The largest risk factor for age-related macular degeneration (ARMD) is advanced age. A
prominent age-related change in the human retina is the accumulation of histochemically …
prominent age-related change in the human retina is the accumulation of histochemically …
[HTML][HTML] Epithelial-mesenchymal transition and proliferation of retinal pigment epithelial cells initiated upon loss of cell-cell contact
Purpose.: Molecular mechanisms that initiate epithelial-mesenchymal transition (EMT)
involved in ocular fibrotic complications remain elusive. Studies were conducted to examine …
involved in ocular fibrotic complications remain elusive. Studies were conducted to examine …
Cell replacement and visual restoration by retinal sheet transplants
MJ Seiler, RB Aramant - Progress in retinal and eye research, 2012 - Elsevier
Retinal diseases such as age-related macular degeneration (ARMD) and retinitis
pigmentosa (RP) affect millions of people. Replacing lost cells with new cells that connect …
pigmentosa (RP) affect millions of people. Replacing lost cells with new cells that connect …
Endogenous and exogenous regulation of redox homeostasis in retinal pigment epithelium cells: An updated antioxidant perspective
Y Markitantova, V Simirskii - International Journal of Molecular Sciences, 2023 - mdpi.com
The retinal pigment epithelium (RPE) performs a range of necessary functions within the
neural layers of the retina and helps ensure vision. The regulation of pro-oxidative and …
neural layers of the retina and helps ensure vision. The regulation of pro-oxidative and …
An eye on age-related macular degeneration: the role of microRNAs in disease pathology
Age-related macular degeneration (AMD) is the primary cause of blindness in developed
countries, and is the third leading cause worldwide. Emerging evidence suggests that …
countries, and is the third leading cause worldwide. Emerging evidence suggests that …
Primordium of an artificial Bruch's membrane made of nanofibers for engineering of retinal pigment epithelium cell monolayers
PH Warnke, M Alamein, S Skabo, S Stephens… - Acta biomaterialia, 2013 - Elsevier
Transplanted retinal pigment epithelium (RPE) cells hold promise for treatment of age-
related macular degeneration (AMD) and Stargardt disease (SD), but it is conceivable that …
related macular degeneration (AMD) and Stargardt disease (SD), but it is conceivable that …
Delivery strategies for treatment of age-related ocular diseases: From a biological understanding to biomaterial solutions
Age-related ocular diseases, such as age-related macular degeneration (AMD), diabetic
retinopathy, and glaucoma, result in life-long functional deficits and enormous global health …
retinopathy, and glaucoma, result in life-long functional deficits and enormous global health …