The first tetraspanins were discovered on surface of human leucocytes, but it was rapidly
demonstrated that they had a wider tissue expression. Twenty-six molecules display …

The transmembrane proteins of the tetraspanin superfamily are implicated in a diverse
range of biological phenomena, including cell motility, metastasis, cell proliferation and …

Abstract CD9, CD63, CD81, and CD82 are glycoproteins of unknown function which belong
to the tetraspan superfamily. These molecules have short cytoplasmic sequences, four …

Publisher Summary This chapter focuses on two sets of molecules involved in the
proliferation and differentiation of highly purified human B lymphocytes: the molecules …

It has recently been shown that several members of the tetraspan superfamily, including
CD9 and CD63, associate with each other and with β1 integrins. In this study, we examined …

The mammalian bladder epithelium elaborates, as a terminal differentiation product, a
specialized plasma membrane called asymmetric unit membrane (AUM) which is believed …

The CD9 antigen was described originally as a 24-kDa surface protein of non-T acute
lymphoblastic leukemia cells and developing B-lymphocytes. It is also strongly expressed on …

Tetraspanin proteins form signaling complexes between them and with other membrane
proteins and modulate cell adhesion and migration properties. The surface expression of …

Publisher Summary The chapter reviews recent findings on the biology of the eosinophil,
particularly distinctive eosinophil features, and discusses the possible role of the eosinophil …

Normal immune responses to primary protein Ags (those not seen previously by the immune
system) have been shown to require C3 and the C3 receptor CR2 (CD21). This investigation …