Inflammaging as a common ground for the development and maintenance of sarcopenia, obesity, cardiomyopathy and dysbiosis

G Livshits, A Kalinkovich - Ageing research reviews, 2019 - Elsevier
Sarcopenia, obesity and their coexistence, obese sarcopenia (OBSP) as well as
atherosclerosis-related cardio-vascular diseases (ACVDs), including chronic heart failure …

[HTML][HTML] Adipose tissue development and lipid metabolism in the human fetus: The 2020 perspective focusing on maternal diabetes and obesity

G Desoye, E Herrera - Progress in lipid research, 2021 - Elsevier
During development, the human fetus accrues the highest proportion of fat of all mammals.
Precursors of fat lobules can be found at week 14 of pregnancy. Thereafter, they expand …

A cross-talk between sestrins, chronic inflammation and cellular senescence governs the development of age-associated sarcopenia and obesity

G Livshits, A Kalinkovich - Ageing Research Reviews, 2023 - Elsevier
The rapid increase in both the lifespan and proportion of older adults is accompanied by the
unprecedented rise in age-associated chronic diseases, including sarcopenia and obesity …

[HTML][HTML] ChemR23 signaling ameliorates cognitive impairments in diabetic mice via dampening oxidative stress and NLRP3 inflammasome activation

J Zhang, L Liu, Y Zhang, Y Yuan, Z Miao, K Lu… - Redox biology, 2022 - Elsevier
Diabetes mellitus is associated with cognitive impairment characterized by memory loss and
cognitive inflexibility. Recent studies have revealed that ChemR23 is implicated in both …

Is depression the missing link between inflammatory mediators and cancer?

B Polityńska, O Pokorska, AM Wojtukiewicz… - Pharmacology & …, 2022 - Elsevier
Patients with cancer are at greater risk of developing depression in comparison to the
general population and this is associated with serious adverse effects, such as poorer …

Role of specialized pro-resolving lipid mediators in pulmonary inflammation diseases: Mechanisms and development

A Yang, Y Wu, G Yu, H Wang - Respiratory Research, 2021 - Springer
Inflammation is an essential mechanism of various diseases. The development and
resolution of inflammation are complex immune-modulation processes which induce the …

Role and mechanism of specialized pro-resolving mediators in obesity-associated insulin resistance

X Liu, Y Tang, Y Luo, Y Gao, L He - Lipids in Health and Disease, 2024 - Springer
With the changing times, obesity has become a characteristic epidemic in the context of the
current era. Insulin resistance (IR) is most commonly caused by obesity, and IR is a common …

Macrophage immunomodulation in chronic osteolytic diseases—The case of periodontitis

C Sima, A Viniegra, M Glogauer - Journal of leukocyte biology, 2019 - academic.oup.com
Periodontitis (PD) is a chronic osteolytic disease that shares pathogenic inflammatory
features with other conditions associated with nonresolving inflammation. A hallmark of PD …

Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner

A Pal, AE Al‐Shaer, W Guesdon, MJ Torres… - The FASEB …, 2020 - Wiley Online Library
Eicosapentaenoic acid (EPA) has garnered attention after the success of the REDUCE‐IT
trial, which contradicted previous conclusions on EPA for cardiovascular disease risk. Here …

[HTML][HTML] Future applications of exosomes delivering resolvins and cytokines in facilitating diabetic foot ulcer healing

JPB Littig, R Moellmer, DK Agrawal… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Type 2 diabetes mellitus (T2DM) increases the risk of many lethal and debilitating
conditions. Among them, foot ulceration due to neuropathy, vascular disease, or trauma …