MicroRNA: function, detection, and bioanalysis

H Dong, J Lei, L Ding, Y Wen, H Ju, X Zhang - Chemical reviews, 2013 - ACS Publications
Mature microRNAs (miRNAs) are a class of evolutionally conserved, single-stranded, small
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …

Circulating cell-free nucleic acids: characteristics and applications

O Pös, O Biró, T Szemes, B Nagy - European Journal of Human …, 2018 - nature.com
Liquid biopsy is becoming a very popular sample obtaining procedure, replacing the
invasive sampling methods for the diagnostic protocols. The advantages of this method …

The majority of microRNAs detectable in serum and saliva is concentrated in exosomes

A Gallo, M Tandon, I Alevizos, GG Illei - PloS one, 2012 - journals.plos.org
There is an increasing interest in using microRNAs (miRNA) as biomarkers in autoimmune
diseases. They are easily accessible in many body fluids but it is controversial if they are …

Updates on liquid biopsy: Current trends and future perspectives for clinical application in solid tumors

P Pinzani, V D'Argenio, M Del Re… - Clinical Chemistry and …, 2021 - degruyter.com
Despite advances in screening and therapeutics cancer continues to be one of the major
causes of morbidity and mortality worldwide. The molecular profile of tumor is routinely …

[HTML][HTML] Circulating RNAs in prostate cancer patients

V Mugoni, Y Ciani, C Nardella, F Demichelis - Cancer letters, 2022 - Elsevier
Growing bodies of evidence have demonstrated that the identification of prostate cancer
(PCa) biomarkers in the patients' blood and urine may remarkably improve PCa diagnosis …

A comprehensive profile of circulating RNAs in human serum

SU Umu, H Langseth, C Bucher-Johannessen… - RNA biology, 2018 - Taylor & Francis
Non-coding RNA (ncRNA) molecules have fundamental roles in cells and many are also
stable in body fluids as extracellular RNAs. In this study, we used RNA sequencing (RNA …

Plasma cell-free RNA characteristics in COVID-19 patients

Y Wang, J Li, L Zhang, HX Sun, Z Zhang, J Xu… - Genome …, 2022 - genome.cshlp.org
The pathogenesis of COVID-19 is still elusive, which impedes disease progression
prediction, differential diagnosis, and targeted therapy. Plasma cell-free RNAs (cfRNAs) …

Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing

C Lässer, GV Shelke, A Yeri, DK Kim, R Crescitelli… - RNA biology, 2017 - Taylor & Francis
Cells secrete extracellular RNA (exRNA) to their surrounding environment and exRNA has
been found in many body fluids such as blood, breast milk and cerebrospinal fluid. However …

Lipoprotein carriers of microRNAs

DL Michell, KC Vickers - Biochimica et Biophysica Acta (BBA)-Molecular …, 2016 - Elsevier
Lipoproteins, namely high-density lipoproteins (HDL), transport a wide-variety of cargo in
addition to cholesterol and lipids. In 2011, HDL and low-density lipoproteins (LDL) were …

Comparison of methods for miRNA extraction from plasma and quantitative recovery of RNA from cerebrospinal fluid

MA McAlexander, MJ Phillips, KW Witwer - Frontiers in genetics, 2013 - frontiersin.org
Interest in extracellular RNA (exRNA) has intensified as evidence accumulates that these
molecules may be useful as indicators of a wide variety of biological conditions. To establish …