Antifungal therapy for systemic mycosis and the nanobiotechnology era: improving efficacy, biodistribution and toxicity

ACO Souza, AC Amaral - Frontiers in Microbiology, 2017 - frontiersin.org
Fungal diseases have been emerging as an important public health problem worldwide with
the increase in host predisposition factors due to immunological dysregulations …

[HTML][HTML] Sol-gel synthesis of thorn-like ZnO nanoparticles endorsing mechanical stirring effect and their antimicrobial activities: Potential role as nano-antibiotics

MF Khan, AH Ansari, M Hameedullah, E Ahmad… - Scientific reports, 2016 - nature.com
The effect of mechanical stirring on sol-gel synthesis of thorn-like ZnO nanoparticles (ZnO-
NPs) and antimicrobial activities is successfully reported in this study. The in-house …

Nanotechnology approaches for delivery and targeting of Amphotericin B in fungal and parasitic diseases

M Jafari, SS Abolmaali, AM Tamaddon… - …, 2021 - Taylor & Francis
Amphotericin B (AMB), with widespread antifungal and anti-parasitic activities and low cross-
resistance with other drugs, has long been identified as a potent antimicrobial drug …

[HTML][HTML] Lung cancer therapy using doxorubicin and curcumin combination: Targeted prodrug based, pH sensitive nanomedicine

Y Hong, S Che, B Hui, Y Yang, X Wang, X Zhang… - Biomedicine & …, 2019 - Elsevier
Lung cancer is the leading cause of cancer death worldwide. To overcome the toxic side
effects and multidrug resistance (MDR) during doxorubicin (DOX) chemotherapy, a …

Anticancer effect of zinc oxide nanoparticles prepared by varying entry time of ion carriers against A431 skin cancer cells in vitro

AY Aljohar, G Muteeb, Q Zia, S Siddiqui, M Aatif… - Frontiers in …, 2022 - frontiersin.org
Although, zinc oxide nanoparticles (ZRTs) as an anti-cancer agent have been the subject of
numerous studies, none of the reports has investigated the impact of the reaction entry time …

Targeted therapy for hepatocellular carcinoma: co-delivery of sorafenib and curcumin using lactosylated pH-responsive nanoparticles

Y Bian, D Guo - Drug design, development and therapy, 2020 - Taylor & Francis
Purpose Hepatocellular carcinoma (HCC) is a leading cancer worldwide. In the present
investigation, sorafenib (SFN) and curcumin (CCM) were co-delivered using pH-sensitive …

[HTML][HTML] Chitosan functionalized poly (ε-caprolactone) nanoparticles for amphotericin B delivery

RGJV Marcano, TT Tominaga, NM Khalil… - Carbohydrate …, 2018 - Elsevier
Amphotericin B (AmB) is a broad-spectrum antifungal drug used in the treatment of fungal
invasive infections. However, its clinical use has been limited due to its side effects and …

Husk-like zinc oxide nanoparticles induce apoptosis through ROS generation in epidermoid carcinoma cells: effect of incubation period on sol-gel synthesis and anti …

WA Alhoqail, AS Alothaim, M Suhail, D Iqbal, M Kamal… - Biomedicines, 2023 - mdpi.com
This study effectively reports the influence of experimental incubation period on the sol-gel
production of husk-like zinc oxide nanoparticles (ZNPs) and their anti-cancerous abilities …

Biomimetically engineered Amphotericin B nano-aggregates circumvent toxicity constraints and treat systemic fungal infection in experimental animals

Q Zia, O Mohammad, MA Rauf, W Khan, S Zubair - Scientific reports, 2017 - nature.com
Biomimetic synthesis of nanoparticles offers a convenient and bio friendly approach to
fabricate complex structures with sub-nanometer precision from simple precursor …

Drug delivery applications of poly-γ-glutamic acid

OA Balogun-Agbaje, OA Odeniyi… - Future Journal of …, 2021 - Springer
Background Poly-γ-glutamic acid (γ-PGA) is a biopolymer of microbial origin, consisting of
repeating units of l-glutamic acid and/or D-glutamic acid. The biopolymer has found use in …