Abstract The Ca2+-sensing receptor (CaSR) is a dimeric family CG protein-coupled receptor
that is expressed in calcitropic tissues such as the parathyroid glands and the kidneys and …

Calcium is an essential trace element and a vital contributor to numerous reactions in
virtually every human cell. To ensure normal physiologic functions, intracellular and …

Alternatives to antibiotics for preventing diarrhea in early-weaned farm animals are sorely
needed. CM piglets (a native Chinese breed) are more resistant to early-weaning stress …

Diarrhoeal disease remains a major health burden worldwide. Secretory diarrhoeas are
caused by certain bacterial and viral infections, inflammatory processes, drugs and genetic …

The Calcium-Sensing Receptor (CaSR) is a member of the class C of G-proteins coupled
receptors (GPCRs), it plays a pivotal role in calcium homeostasis by directly controlling …

The calcium-sensing receptor (CaSR) is a class CG protein–coupled receptor that responds
to multiple endogenous agonists and allosteric modulators, including divalent and trivalent …

Calcium balance is essential for a multitude of physiological processes, ranging from cell
signaling to maintenance of bone health. Adequate intestinal absorption of calcium is a …

Cholera is a global health problem with no targeted therapies. The Ca2+-sensing receptor
(CaSR) is a regulator of intestinal ion transport and a therapeutic target for diarrhea, and …

The calcium sensing receptor (CaSR) is a class C G-protein-coupled receptor that is crucial
for the feedback regulation of extracellular free ionised calcium homeostasis. While …

Background The calcium-sensing receptor (CaSR) in the distal convoluted tubule (DCT)
activates the NaCl cotransporter (NCC). Glucose acts as a positive allosteric modulator of …