Cell death maintains cell morphology and homeostasis during development by removing
damaged or obsolete cells. The concentration of metal ions whithin cells is regulated by …

Mitochondria, traditionally recognized as cellular'powerhouses' due to their pivotal role in
energy production, have emerged as multifunctional organelles at the intersection of …

Myocardial dysfunction is a frequent complication in patients with severe sepsis. However,
effective drugs for the prevention of myocardial dysfunction and the molecular mechanisms …

Tumor therapy presents significant challenges, and conventional treatments exhibit limited
therapeutic effectiveness. Imbalance of calcium homeostasis as a key cause of tumor cell …

Amyotrophic lateral sclerosis (ALS) is considered a fatal progressive degeneration of motor
neurons (MN) caused by oxidative stress and mitochondrial dysfunction. There are currently …

Inositol 1, 4, 5-trisphosphate receptors (IP3Rs) play a crucial role in maintaining
intracellular/cytosolic calcium ion (Ca2+ i) homeostasis. The release of Ca2+ from IP3Rs …

Hydroxyapatite nanoparticles (nHA) have gained attention as potential intracellular drug
delivery vehicles due to their high binding affinity for various biomolecules and pH …

Necroptosis is considered a programmed necrosis that requires receptor-interacting protein
kinase 1 (RIPK1), receptor-interacting protein kinase 3 (RIPK3), and pore-forming mixed …

Perioperative neurocognitive disorder (PND) is a common complication of surgical
anesthesia, yet its precise etiology remains unclear. Neuroinflammation is a key feature of …

The field of ferroptosis research has grown exponentially since this form of cell death was
first identified over a decade ago. Ferroptosis, an iron-and ROS-dependent type of cell …