Aging is a multifaceted and complicated process, manifested by a decline of normal
physiological functions across tissues and organs, leading to overt frailty, mortality, and …

Adipose tissue derived stem cells (ADSCs) are mesenchymal stem cells identified within
subcutaneous tissue at the base of the hair follicle (dermal papilla cells), in the dermal …

Background Adult mesenchymal stem cells (MSCs) hold great promise for regenerative
medicine because of their self-renewal, multipotency, and trophic and immunosuppressive …

Mesenchymal stem cells (MSCs) are multipotent cells capable of self-renewal and
differentiation. There is increasing evidence of the therapeutic value of MSCs in various …

Various source-derived mesenchymal stem cells (MSCs) have been considered for cell
therapeutics in incurable diseases. To characterize MSCs from different sources, we …

Complex interactions among cells of the monocyte-macrophage-osteoclast lineage and the
mesenchymal stem cell-osteoblast lineage play a major role in the pathophysiology of bone …

This review describes the historical emergence of the concept of bone marrow
mesenchymal stem cells (MSCs), summarizing data on Wolf and Trentin's hematopoietic …

The roles of Oct4 and Nanog in maintaining self-renewal and undifferentiated status of adult
stem cells are unclear. Here, increase in Oct4 and Nanog expression along with increased …

Abstract More than 2.1 million age-related fractures occur in the United States annually,
resulting in an immense socioeconomic burden. Importantly, the age-related deterioration of …

Mesenchymal stem/stromal cells (MSC) show widespread application for a variety of clinical
conditions; therefore, their use necessitates continuous monitoring of their safety. The risk …