The CNS critically relies on the formation and proper function of its vasculature during
development, adult homeostasis and disease. Angiogenesis—the formation of new blood …

Angiogenesis is the growth of new capillaries from the preexisting blood vessels.
Glioblastoma (GBM) tumors are highly vascularized tumors, and glioma growth depends on …

Tumor growth and metastasis rely on tumor vascular network for the adequate supply of
oxygen and nutrients. Tumor angiogenesis relies on a highly complex program of growth …

The extracellular matrix (ECM) is a complex network of extracellular-secreted
macromolecules, such as collagen, enzymes and glycoproteins, whose main functions deal …

Non-melanoma skin cancers (NMSCs) include basal cell carcinoma (BCC), squamous cell
carcinoma (SCC) and Merkel cell carcinoma (MCC). These neoplasms are highly diverse in …

Neutrophils are the most abundant leukocytes in blood and are considered to be the first line
of defense during inflammation and infections. In addition, neutrophils are also found …

Metastasis is a distinct stage of cancer progression that requires the development of
angiogenic blood vessels serving as conduits for tumor cell dissemination. An accumulated …

Many studies have recently used several deep learning methods for detecting skin cancer.
However, hyperspectral imaging (HSI) is a noninvasive optics system that can obtain …

Matrix metalloproteinases are versatile endopeptidases with many different functions in the
body in health and disease. In the brain, matrix metalloproteinases are critical for tissue …

Endothelial cell migration is essential to angiogenesis. This motile process is directionally
regulated by chemotactic, haptotactic, and mechanotactic stimuli and further involves …