The population doctrine in cognitive neuroscience

RB Ebitz, BY Hayden - Neuron, 2021 - cell.com
A major shift is happening within neurophysiology: a population doctrine is drawing level
with the single-neuron doctrine that has long dominated the field. Population-level ideas …

Going beyond primary motor cortex to improve brain–computer interfaces

JA Gallego, TR Makin, SD McDougle - Trends in neurosciences, 2022 - cell.com
Brain–computer interfaces (BCIs) for movement restoration typically decode the user's intent
from neural activity in their primary motor cortex (M1) and use this information to enable …

Preserved neural dynamics across animals performing similar behaviour

M Safaie, JC Chang, J Park, LE Miller, JT Dudman… - Nature, 2023 - nature.com
Animals of the same species exhibit similar behaviours that are advantageously adapted to
their body and environment. These behaviours are shaped at the species level by selection …

Motor cortex activity across movement speeds is predicted by network-level strategies for generating muscle activity

S Saxena, AA Russo, J Cunningham, MM Churchland - Elife, 2022 - elifesciences.org
Learned movements can be skillfully performed at different paces. What neural strategies
produce this flexibility? Can they be predicted and understood by network modeling? We …

Rethinking brain-wide interactions through multi-region 'network of networks' models

MG Perich, K Rajan - Current opinion in neurobiology, 2020 - Elsevier
Highlights•Brains can be viewed as a composition of anatomically distinct modules called
regions.•Brain regions interact in complex ways to form a 'network of networks'.•Untangling …

Measurement, manipulation and modeling of brain-wide neural population dynamics

KV Shenoy, JC Kao - Nature communications, 2021 - nature.com
Neural recording technologies increasingly enable simultaneous measurement of neural
activity from multiple brain areas. To gain insight into distributed neural computations, a …

Rotational dynamics in motor cortex are consistent with a feedback controller

HT Kalidindi, KP Cross, TP Lillicrap, M Omrani… - Elife, 2021 - elifesciences.org
Recent studies have identified rotational dynamics in motor cortex (MC), which many
assume arise from intrinsic connections in MC. However, behavioral and neurophysiological …

Inferring brain-wide interactions using data-constrained recurrent neural network models

MG Perich, C Arlt, S Soares, ME Young, CP Mosher… - BioRxiv, 2020 - biorxiv.org
Behavior arises from the coordinated activity of numerous anatomically and functionally
distinct brain regions. Modern experimental tools allow unprecedented access to large …

Targeted neural dynamical modeling

C Hurwitz, A Srivastava, K Xu, J Jude… - Advances in …, 2021 - proceedings.neurips.cc
Latent dynamics models have emerged as powerful tools for modeling and interpreting
neural population activity. Recently, there has been a focus on incorporating simultaneously …

Small, correlated changes in synaptic connectivity may facilitate rapid motor learning

B Feulner, MG Perich, RH Chowdhury, LE Miller… - Nature …, 2022 - nature.com
Animals rapidly adapt their movements to external perturbations, a process paralleled by
changes in neural activity in the motor cortex. Experimental studies suggest that these …