The diversity of biomolecules present in plasmid DNA (pDNA)-containing extracts and the
structural and chemical similarities between pDNA and impurities are some of the main …

Pseudobiospecific ligand affinity chromatography is based on the use of robust and
inexpensive substitutes for the biological ligands used in biospecific ligand affinity …

A novel DNA solid-phase extraction protocol based on the pH-dependent charge of chitosan
was developed specifically for low-volume DNA extraction on microchips. The method uses …

Plasmid DNA (pDNA)-based vaccines offer more rapid avenues for development and
production if compared to those of conventional virus-based vaccines. They do not rely on …

This review describes the role of affinity chromatography in large-scale protein purification.
The currently available affinity supports are examined with respect to their use in the …

Reactive monoliths of macroporous poly (glycidyl methacrylate‐co‐ethylene dimethacrylate)
have been prepared by “in‐situ” copolymerization of the monomers in the presence of …

The ability to isolate sc (supercoiled) pDNA (plasmid DNA) isoform should be one of the
features of a pDNA purification process, eliminating sample contaminants such as RNA …

This volume is devoted to the developments in the branch of polymer chemistry which deals
with immobilized systems. These systems are widely used in fields connected with …

The recent developments in molecular therapies, such as nonviral gene therapy and DNA
vaccination, have fostered the development of eYcient plasmid DNA (pDNA) 1 purification …

The growing demand on plasmid DNA (pDNA) manufacture for therapeutic applications
requires a final product with higher quality and quantity, spending the least time. Most of the …