Acute pancreatitis (AP) is an inflammatory disease with varied severity, ranging from mild
local inflammation to severe systemic involvement resulting in substantial mortality. Early …

Autoimmune pancreatitis (AIP) is a form of chronic pancreatitis characterised clinically by
frequent presentation with obstructive jaundice, histologically by a lymphoplasmacytic …

Objective In patients with pancreatitis, early persisting organ failure is believed to be the
most important cause of mortality. This study investigates the relation between the timing …

Background & Aims Pancreatitis starts with primarily sterile local inflammation that induces
systemic inflammatory response syndrome, followed by compensatory anti-inflammatory …

Background & Aims Acute pancreatitis is characterized by premature intracellular activation
of digestive proteases within pancreatic acini and a consecutive systemic inflammatory …

NLRP3 inflammasome is a multiprotein complex expressed in a variety of cells to stimulate
the production of inflammatory factors. Activation of NLRP3 inflammasome depends on a …

Acute pancreatitis is an inflammatory process of the pancreatic gland that eventually may
lead to a severe systemic inflammatory response. A key event in pancreatic damage is the …

Background Severe acute pancreatitis (SAP) with severe complications such as multiple
organ failure, necrosis, abscess, and formation of pancreatic pseudocysts often gives rise to …

Acute pancreatitis (AP) is a common emergency condition. In the majority of cases, it
presents in a mild and self‐limited form. However, about 20% of patients develop severe …

OBJECTIVES: Severe acute pancreatitis (SAP) is still a big challenge. Accumulated data
showed that overexpression of cyclooxygenase-2 (COX-2) in acute pancreatitis and …