Scaffold fabrication technologies and structure/function properties in bone tissue engineering

MN Collins, G Ren, K Young, S Pina… - Advanced functional …, 2021 - Wiley Online Library
Bone tissue engineering (BTE) is a rapidly growing field aiming to create a biofunctional
tissue that can integrate and degrade in vivo to treat diseased or damaged tissue. It has …

The osteosarcoma microenvironment: a complex but targetable ecosystem

I Corre, F Verrecchia, V Crenn, F Redini, V Trichet - Cells, 2020 - mdpi.com
Osteosarcomas are the most frequent primary bone sarcomas, affecting mainly children,
adolescents, and young adults, and with a second peak of incidence in elderly individuals …

Strategies for bone regeneration: from graft to tissue engineering

G Battafarano, M Rossi, V De Martino… - International journal of …, 2021 - mdpi.com
Bone is a regenerative organ characterized by self-renewal ability. Indeed, it is a very
dynamic tissue subjected to continuous remodeling in order to preserve its structure and …

[HTML][HTML] Single-cell RNA landscape of the osteoimmunology microenvironment in periodontitis

Y Chen, H Wang, Q Yang, W Zhao, Y Chen, Q Ni… - Theranostics, 2022 - ncbi.nlm.nih.gov
Single-cell RNA sequencing (scRNA-seq) enables specific profiling of cell populations at
single-cell resolution. The osteoimmunology microenvironment in the occurrence and …

[HTML][HTML] Immunomodulatory bioactive glasses for tissue regeneration

K Zheng, W Niu, B Lei, AR Boccaccini - Acta Biomaterialia, 2021 - Elsevier
The regulatory functions of the immune response in tissue healing, repair, and regeneration
have been evidenced in the last decade. Immune cells play central roles in immune …

Immunomodulatory strategies for bone regeneration: a review from the perspective of disease types

N Su, C Villicana, F Yang - Biomaterials, 2022 - Elsevier
Tissue engineering strategies for treating bone loss to date have largely focused on
targeting stem cells or vascularization. Immune cells, including macrophages and T cells …

Toward a better regeneration through implant‐mediated immunomodulation: harnessing the immune responses

B Zhang, Y Su, J Zhou, Y Zheng, D Zhu - Advanced science, 2021 - Wiley Online Library
Tissue repair/regeneration, after implantation or injury, involves comprehensive
physiological processes wherein immune responses play a crucial role to enable tissue …

[HTML][HTML] Exosome-functionalized polyetheretherketone-based implant with immunomodulatory property for enhancing osseointegration

L Fan, P Guan, C Xiao, H Wen, Q Wang, C Liu, Y Luo… - Bioactive materials, 2021 - Elsevier
The host immune response effecting on biomaterials is critical to determine implant fates
and bone regeneration property. Bone marrow stem cells (BMSCs) derived exosomes …

Modulation of immune-inflammatory responses through surface modifications of biomaterials to promote bone healing and regeneration

F Batool, H Özçelik, C Stutz… - Journal of Tissue …, 2021 - journals.sagepub.com
Control of inflammation is indispensable for optimal oral wound healing and tissue
regeneration. Several biomaterials have been used to enhance the regenerative outcomes; …

Inflammation and biomaterials: role of the immune response in bone regeneration by inorganic scaffolds

JM Sadowska, MP Ginebra - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
The regulatory role of the immune system in maintaining bone homeostasis and restoring its
functionality, when disturbed due to trauma or injury, has become evident in recent years …