Hypoxia is an integral component of the tumor microenvironment. Either as chronic or
cycling hypoxia, it exerts a similar effect on cancer processes by activating hypoxia-inducible …

Endometriosis is a common gynecologic disease defined as the presence of ectopic
endometrial tissues on the ovaries and pelvic peritoneum, and it is a significant cause of …

HIV infection of astrocytes leads to restricted gene expression and replication but abundant
expression of HIV early genes Tat, Nef and Rev. A great deal of neuroHIV research has so …

Objective: This study aimed to investigate the role of squamous cell carcinoma antigen
recognized by T cells 3 (SART3) in hepatocellular carcinoma (HCC). Methods: SART3 …

Background: Notch signaling is indicated as novel therapeutic targets to prevent recurrence
of breast cancer. LncRNAs were identified as downstream target of Notch pathway …

Osteosarcoma is a common, high-risk primary bone malignancy that mostly affects the
younger population. There has been no marked improvement in the clinical outcomes of …

Hematopoietic stem cells (HSCs) possess the potential for self-renew and the capacity,
throughout life, to differentiate into all blood cell lineages. Yet, the mechanistic basis for HSC …

Tip110, an important regulator of several oncogenic proteins, was significantly
downregulated in human metastatic melanoma cells exposed to a hypoxic condition …

The four jointed box 1 (FJX1) is a regulator of angiogenesis, and the levels of FJX1 are
increased in several types of cancer. Angiogenesis plays a critical role in endometrial …

HIV-1 Tat-interacting protein of 110 kDa (Tip110), also referred to as squamous cell
carcinoma antigen recognized by T cells 3 (Sart3), p110 or p110 nrb, was initially identified …