The rise in antimicrobial resistant bacteria threatens the current methods utilized to treat
bacterial infections. The development of novel therapeutic agents is crucial in avoiding a …

Tuberculosis (TB) is one of the leading cause of death worldwide, and the world is fighting
with this global health emergency from the past 25 year. The current clinical interventions for …

Tuberculosis (TB) presently accounts for high global mortality and morbidity rates, despite
the introduction four decades ago of the affordable and efficient four-drugs (isoniazid …

Tuberculosis (TB) continues to be a devastating infectious disease and remerges as a
global health emergency due to an alarming rise of antimicrobial resistance to its treatment …

The upsurge of drug resistant tuberculosis is major health threat globally. To counteract,
antimicrobial peptides are being explored as possible alternatives. However, certain …

In metal-peptide interactions, cations form stable complexes through bonds with
coordinating groups as side chains of amino acids. These compounds, among other things …

Human cathelicidin antimicrobial peptide LL-37 (LL-37) is an antimicrobial peptide derived
from its precursor protein hCAP18, which is an only cathelicidin in human. LL-37 not only …

Increasing experimental evidence supports the idea that Mycobacterium tuberculosis has
evolved strategies to survive within lysosomes of activated macrophages. To further our …

Porcine epidemic diarrhea virus (PEDV) is a harmful coronavirus infecting pigs, which is
resulting in substantial financial losses in the global pig industry. The lack of effective …

The ineffectiveness of anti-tuberculous therapy against dormant and drug-resistant
mycobacteria demands scrutiny of alternative candidates like antimicrobial peptides having …