Dose-response for assessing the cancer risk of inorganic arsenic in drinking water: the scientific basis for use of a threshold approach

JS Tsuji, ET Chang, PR Gentry, HJ Clewell… - Critical reviews in …, 2019 - Taylor & Francis
The biologic effects of inorganic arsenic predominantly involve reaction of the trivalent forms
with sulfhydryl groups in critical proteins in target cells, potentially leading to various …

Heavy metal exposure and cardiovascular disease

Z Pan, T Gong, P Liang - Circulation Research, 2024 - Am Heart Assoc
Heavy metals are harmful environmental pollutants that have attracted widespread attention
due to their health hazards to human cardiovascular disease. Heavy metals, including lead …

Physiologically based pharmacokinetic modeling for chlorinated paraffins in rats and humans: importance of biliary excretion

Z Dong, T Li, Y Wan, Y Sun, J Hu - Environmental Science & …, 2019 - ACS Publications
Chlorinated paraffins (CPs) are chemicals with high production volumes that can
accumulate at high levels in general populations. The pharmacokinetics of CPs as pollutants …

[HTML][HTML] A mass-balance approach to evaluate arsenic intake and excretion in different populations

D Beene, P Collender, A Cardenas, C Harvey… - Environment …, 2022 - Elsevier
Unless a toxicant builds up in a deep compartment, intake by the human body must on
average balance the amount that is lost. We apply this idea to assess arsenic (As) exposure …

Arsenic contamination of irrigation wells and associated human health hazards in the Punjab plains of Pakistan

A Javed, ZU Baig, A Farooqi - Environmental Technology & Innovation, 2021 - Elsevier
In the present study, the tubewell water quality, emphasizing on As contamination, were
investigated in the Punjab plains of Pakistan. The Na-Cl water type is dominated in Doabs …

A mass-balance model to assess arsenic exposure from multiple wells in Bangladesh

LB Huhmann, CF Harvey, A Navas-Acien… - Journal of exposure …, 2022 - nature.com
Abstract Background Water arsenic (As) sources beyond a rural household's primary well
may be a significant source for certain individuals, including schoolchildren and men …

Chronic arsenic exposure affects stromal cells and signaling in the small intestine in a sex-specific manner

SW Ventrello, NR McMurry, NM Edwards… - Toxicological …, 2024 - academic.oup.com
Arsenic is a toxicant that is ingested through drinking water and food, exposing nearly 140
million people to levels above the 10 ppb guideline concentration. Studies have shown that …

Rational use of medicines in neonates: current observations, areas for research and perspectives

K Allegaert - Healthcare, 2018 - mdpi.com
A focused reflection on rational medicines use in neonates is valuable and relevant,
because indicators to assess rational medicines use are difficult to apply to neonates …

[HTML][HTML] Transcriptome responses in blood reveal distinct biological pathways associated with arsenic exposure through drinking water in rural settings of Punjab …

MYA Rehman, M van Herwijnen, J Krauskopf… - Environment …, 2020 - Elsevier
Abstract Background Groundwater Arsenic (As) contamination is a global public health
concern responsible for various health implications and a neglected area of environmental …

Arsenic risk assessment

JS Lee, JA Davis - Handbook of arsenic toxicology, 2023 - Elsevier
Inorganic arsenic (iAs) is a naturally occurring metalloid found in soil, bedrock, and water.
Individuals worldwide are unknowingly exposed to arsenic through ingestion of …