Principles and applications of nucleic acid strand displacement reactions

FC Simmel, B Yurke, HR Singh - Chemical reviews, 2019 - ACS Publications
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …

Point-of-care diagnostic tests for tuberculosis disease

JM Hong, H Lee, NV Menon, CT Lim, LP Lee… - Science translational …, 2022 - science.org
Rapid diagnosis is one key pillar to end tuberculosis (TB). Point-of-care tests (POCTs)
facilitate early detection, immediate treatment, and reduced transmission of TB disease. This …

Noble metal nanoparticle biosensors: from fundamental studies toward point-of-care diagnostics

H Geng, S Vilms Pedersen, Y Ma… - Accounts of chemical …, 2022 - ACS Publications
Conspectus Noble metal nanoparticles (NMNPs) have become firmly established as
effective agents to detect various biomolecules with extremely high sensitivity. This ability …

Toehold-mediated biosensors: Types, mechanisms and biosensing strategies

S Li, L Zhu, S Lin, W Xu - Biosensors and Bioelectronics, 2023 - Elsevier
Toehold-mediated strand displacement (TMSD) reactions between double-stranded DNA
and single-stranded oligonucleotides, which use a toehold structure as a switch, enable …

Fluorescence sensing of circulating diagnostic biomarkers using molecular probes and nanoparticles

O Tagit, N Hildebrandt - ACS sensors, 2017 - ACS Publications
The interplay of photonics, nanotechnology, and biochemistry has significantly improved the
identification and characterization of multiple types of biomarkers by optical biosensors …

Quantum dots: from fluorescence to chemiluminescence, bioluminescence, electrochemiluminescence, and electrochemistry

J Yao, L Li, P Li, M Yang - Nanoscale, 2017 - pubs.rsc.org
During the past decade, nanotechnology has become one of the major forces driving basic
and applied research. As a novel class of inorganic fluorochromes, research into quantum …

Genome‐wide host RNA signatures of infectious diseases: discovery and clinical translation

HD Gliddon, JA Herberg, M Levin, M Kaforou - Immunology, 2018 - Wiley Online Library
The use of whole blood gene expression to derive diagnostic biomarkers capable of
distinguishing between phenotypically similar diseases holds great promise but remains a …

Duplex-specific nuclease-amplified detection of MicroRNA using compact quantum dot–DNA conjugates

Y Wang, PD Howes, E Kim, CD Spicer… - … applied materials & …, 2018 - ACS Publications
Advances in nanotechnology have provided new opportunities for the design of next-
generation nucleic acid biosensors and diagnostics. Indeed, combining advances in …

Semiconductor quantum dot FRET: Untangling energy transfer mechanisms in bioanalytical assays

PT Snee - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
Since their development at the turn of the millennium, bright and water-soluble
semiconductor quantum dots (QDs) have been applied in analytical chemistry. QDs serve as …

Current nanotechnological strategies using lipids, carbohydrates, proteins and metal conjugates-based carrier systems for diagnosis and treatment of tuberculosis—A …

N Usharani, SV Kanth, N Saravanan - International Journal of Biological …, 2023 - Elsevier
Tuberculosis is a fatal disease caused by Mycobacterium tuberculosis with highest morbidity
and mortality every year. The evolution of anti-TB drugs is promising in controlling and …