Obesity is growing at an alarming rate, which is characterized by increased adipose tissue. It
increases the probability of many health complications, such as diabetes, arthritis, cardiac …

Privileged structures are widely used in the process of drug design, and provide an effective
template in medicinal chemistry. Diarylheptanoids are a class of structurally distinctive …

Obesity is associated with an increase in adipose tissue, which is mediated by hyperplasia
and hypertrophy. Therefore, inhibiting cell proliferation during mitotic clonal expansion …

Rosiglitazone (RG) is a well‐known activator of peroxisome proliferator‐activated receptor‐
gamma (PPARγ) and used to treat hyperglycemia and type 2 diabetes; however, its clinical …

In this study, methionine sulfoxide (MetO) was identified as an active metabolite that
suppresses adipogenesis after screening obese individuals versus the normal population …

Coumestrol is a natural phytochemical present in plants such as red clover and soy, and has
been reported to stimulate the estrogen receptor as a major phytoestrogen. While the …

Diarylheptanoids from the barks of Alnus viridis ssp. viridis (green alder) and Alnus glutinosa
(black alder) were explored for anti-quorum sensing activity. Chemicals with anti-quorum …

Macrophages and many chemokines are closely associated with the adipogenic
differentiation of bone marrow mesenchymal stem cells (MSCs), but their roles in …

Five new diarylheptanoids, kaemgalangins A–E (1–5), and seven known ones were isolated
from the rhizomes of Kaempferia galanga. The structures of new compounds were identified …

The differentiation of precursor cells into mature adipocytes (adipogenesis) has been an
area of increased focus, spurred by a rise in obesity rates. Though our understanding of …