The role of the indoles in microbiota-gut-brain axis and potential therapeutic targets: A focus on human neurological and neuropsychiatric diseases

Y Zhou, Y Chen, H He, M Peng, M Zeng, H Sun - Neuropharmacology, 2023 - Elsevier
At present, a large number of relevant studies have suggested that the changes in gut
microbiota are related to the course of nervous system diseases, and the microbiota-gut …

The roles of gut microbiota and its metabolites in diabetic nephropathy

H Zhao, CE Yang, T Liu, MX Zhang, Y Niu… - Frontiers in …, 2023 - frontiersin.org
Diabetic nephropathy (DN) is a severe microvascular complication of diabetes, which
increases the risk of renal failure and causes a high global disease burden. Due to the lack …

[HTML][HTML] Microbiota-derived metabolite Indoles induced aryl hydrocarbon receptor activation and inhibited neuroinflammation in APP/PS1 mice

J Sun, Y Zhang, Y Kong, T Ye, Q Yu… - Brain, Behavior, and …, 2022 - Elsevier
Gut microbiota alterations might affect the development of Alzheimer's disease (AD) through
microbiota-derived metabolites. For example, microbiota-derived Indoles via tryptophan …

The potential benefits and controversies of probiotics use in patients at different stages of chronic kidney disease

N Tian, L Li, JKC Ng, PKT Li - Nutrients, 2022 - mdpi.com
The therapeutic modulation of the gut microbiome has been suggested to be one of the tools
in the integrated management of chronic kidney disease (CKD) in recent years …

Microbial-derived tryptophan catabolites, kidney disease and gut inflammation

AM Madella, J Van Bergenhenegouwen, J Garssen… - Toxins, 2022 - mdpi.com
Uremic metabolites, molecules either produced by the host or from the microbiota population
existing in the gastrointestinal tract that gets excreted by the kidneys into urine, have …

The gut microbiome tango in the progression of chronic kidney disease and potential therapeutic strategies

Z Tang, S Yu, Y Pan - Journal of Translational Medicine, 2023 - Springer
Chronic kidney disease (CKD) affects more than 10% population worldwide and becomes a
huge burden to the world. Recent studies have revealed multifold interactions between CKD …

The pathophysiological mechanisms underlying diabetic retinopathy

L Wei, X Sun, C Fan, R Li, S Zhou, H Yu - Frontiers in Cell and …, 2022 - frontiersin.org
Diabetic retinopathy (DR) is the most common complication of diabetes mellitus (DM), which
can lead to visual impairment and even blindness in severe cases. DR is generally …

Role of gut–kidney axis in renal diseases and IgA nephropathy

RC Monteiro, L Berthelot - Current opinion in gastroenterology, 2021 - journals.lww.com
Role of gut–kidney axis in renal diseases and IgA nephropath... : Current Opinion in
Gastroenterology Role of gut–kidney axis in renal diseases and IgA nephropathy : Current …

Gut microbial metabolites SCFAs and chronic kidney disease

M He, W Wei, Y Zhang, Z Xiang, D Peng… - Journal of Translational …, 2024 - Springer
The global incidence of Chronic Kidney Disease (CKD) is steadily escalating, with
discernible linkage to the intricate terrain of intestinal microecology. The intestinal microbiota …

Uremic Toxin-Producing Bacteroides Species Prevail in the Gut Microbiota of Taiwanese CKD Patients: An Analysis Using the New Taiwan Microbiome Baseline

S Shivani, CY Kao, A Chattopadhyay… - Frontiers in Cellular …, 2022 - frontiersin.org
Rationale and Objective Gut microbiota have been targeted by alternative therapies for non-
communicable diseases. We examined the gut microbiota of a healthy Taiwanese …