Bestrophinopathy: an RPE-photoreceptor interface disease
KE Guziewicz, D Sinha, NM Gómez, K Zorych… - Progress in retinal and …, 2017 - Elsevier
Bestrophinopathies, one of the most common forms of inherited macular degenerations, are
caused by mutations in the BEST1 gene expressed in the retinal pigment epithelium (RPE) …
caused by mutations in the BEST1 gene expressed in the retinal pigment epithelium (RPE) …
Lipofuscin, its origin, properties, and contribution to retinal fluorescence as a potential biomarker of oxidative damage to the retina
MB Różanowska - Antioxidants, 2023 - mdpi.com
Lipofuscin accumulates with age as intracellular fluorescent granules originating from
incomplete lysosomal digestion of phagocytosed and autophagocytosed material. The …
incomplete lysosomal digestion of phagocytosed and autophagocytosed material. The …
Label-free hyperspectral imaging and deep-learning prediction of retinal amyloid β-protein and phosphorylated tau
Alzheimer's disease (AD) is a major risk for the aging population. The pathological hallmarks
of AD—an abnormal deposition of amyloid β-protein (Aβ) and phosphorylated tau (pTau) …
of AD—an abnormal deposition of amyloid β-protein (Aβ) and phosphorylated tau (pTau) …
Hyperspectral imaging and the retina: worth the wave?
S Lemmens, J Van Eijgen, K Van Keer… - … vision science & …, 2020 - tvst.arvojournals.org
Purpose: Hyperspectral imaging is gaining attention in the biomedical field because it
generates additional spectral information to study physiological and clinical processes …
generates additional spectral information to study physiological and clinical processes …
Hyperspectral autofluorescence imaging of drusen and retinal pigment epithelium in donor eyes with age-related macular degeneration
Purpose: To elucidate the molecular pathogenesis of age-related macular degeneration
(AMD) and interpretation of fundus autofluorescence imaging, the authors identified spectral …
(AMD) and interpretation of fundus autofluorescence imaging, the authors identified spectral …
Hyperspectral imaging of the retina: a review
Hyperspectral imaging (HSI) is a form of spectral imaging pioneered for remote sensing
satellite imaging in agriculture and water control (Fig. 1). 1 HSI collects data from across the …
satellite imaging in agriculture and water control (Fig. 1). 1 HSI collects data from across the …
In situ morphologic and spectral characterization of retinal pigment epithelium organelles in mice using multicolor confocal fluorescence imaging
RK Meleppat, KE Ronning, SJ Karlen… - … & Visual Science, 2020 - iovs.arvojournals.org
Purpose: To investigate the major organelles of the retinal pigment epithelium (RPE) in wild-
type (WT, control) mice and their changes in pigmented Abca4 knockout (Abca4−/−) mice …
type (WT, control) mice and their changes in pigmented Abca4 knockout (Abca4−/−) mice …
Fundus autofluorescence imaging in patients with choroidal melanoma
A Bindewald-Wittich, FG Holz, T Ach, M Fiorentzis… - Cancers, 2022 - mdpi.com
Simple Summary The ocular fundus contains molecules that emit fluorescence when excited
with light of an appropriate wavelength. Fundus autofluorescence imaging is based on the in …
with light of an appropriate wavelength. Fundus autofluorescence imaging is based on the in …
Clinical applications of non‐invasive multi and hyperspectral imaging of cell and tissue autofluorescence beyond oncology
Hyperspectral and multispectral imaging of cell and tissue autofluorescence employs
fluorescence imaging, without exogenous fluorophores, across multiple excitation/emission …
fluorescence imaging, without exogenous fluorophores, across multiple excitation/emission …
Retinal organoids long-term functional characterization using two-photon fluorescence lifetime and hyperspectral microscopy
Pluripotent stem cell-derived organoid technologies have opened avenues to preclinical
basic science research, drug discovery, and transplantation therapy in organ systems. Stem …
basic science research, drug discovery, and transplantation therapy in organ systems. Stem …