Antiphospholipid antibodies are associated with arterial and venous thrombosis, recurrent pregnancy loss, and thrombocytopenia. Although the antibodies have not been conclusively …
M Blank, I Krause, M Fridkin, N Keller… - The Journal of …, 2002 - Am Soc Clin Investig
The antiphospholipid syndrome (APS) is characterized by the presence of pathogenic autoantibodies against β2-glycoprotein-I (β2GPI). The factors causing production of anti …
E Matsuura, Y Igarashi, T Yasuda, DA Triplett… - The Journal of …, 1994 - rupress.org
Anticardiolipin antibodies (aCL) derived from the sera of individuals exhibiting the antiphospholipid syndrome (APS) directly bind to beta 2-glycoprotein I (beta 2-GPI), which is …
Objective To clarify the association of autoantibodies against prothrombin with the clinical manifestations of the antiphospholipid syndrome (APS) and with the presence of lupus …
Y Hasunuma, E Matsuura, Z Makita… - Clinical & …, 1997 - academic.oup.com
Anticardiolipin antibodies (aCL) in the sera of patients with antiphospholipid syndrome (APS) recognize an altered structure of β2-glycoprotein I (β2-GPI) interacting with solid …
Cardiolipins (CL) represent unique phospholipids of bacteria and eukaryotic mitochondria with four acyl chains and two phosphate groups that have been implicated in numerous …
ANTIPHOSPHOLIPID ANTIBODIES ARE A HETEROGENEOUS GROUP of autoantibodies that are detected by immunoassays and functional coagulation tests. The antigenic targets …
E Matsuura, K Kobayashi, M Tabuchi… - Progress in lipid research, 2006 - Elsevier
Oxidized low-density lipoprotein (oxLDL) is thought to promote atherosclerosis through complex inflammatory and immunologic mechanisms that lead to lipid dysregulation and …
β 2-glycoprotein I (β 2-GPI) is a major antigen for antiphospholipid antibodies (Abs, aPL) present in patients with antiphospholipid syndrome (APS). We recently reported (J. Lipid …