P Qiu, Y Liu, J Zhang - Inflammation, 2019 - Springer
Sepsis is a systemic inflammatory response syndrome caused by infection. The core mechanism underlying sepsis is immune dysfunction, with macrophages, as important cells …
X Ao, L Zou, Y Wu - Cell Death & Differentiation, 2014 - nature.com
Autophagy (macroautophagy) is a highly conserved intracellular and lysosome-dependent degradation process in which autophagic substrates are enclosed and degraded by a …
U Patel, S Rajasingh, S Samanta, T Cao, B Dawn… - Drug discovery today, 2017 - Elsevier
Highlights•This review is focusing on polarization of macrophages by epigenetic modifications.•M1/M2 macrophages are flawlessly synchronized, specialized, and perform …
Y Hu, J Shao, H Dong, D Yang, X Dong - ACS Materials Letters, 2024 - ACS Publications
Programmed cell death (PCD) is crucial for cell renewal, embryogenesis, the immune response, tissue growth regulation, and other essential biological processes. Recent …
A Padhi, K Pattnaik, M Biswas, M Jagadeb… - The Journal of …, 2019 - journals.aai.org
Despite representing a very important class of virulence proteins, the role of lipoproteins in the pathogenesis of Mycobacterium tuberculosis remains elusive. In this study, we …
Y Wu, J Yao, J Xie, Z Liu, Y Zhou, H Pan… - Signal transduction and …, 2018 - nature.com
Autophagy is an evolutionarily conserved catabolic process that eliminates harmful components through lysosomal degradation. In addition to its role in maintaining cellular …
Macrophages are on the front line of host defense. They possess an array of germline‐ encoded pattern recognition receptors/sensors (PRRs) that recognize pathogen‐associated …
D Elshaer, J Begun - Seminars in cell & developmental biology, 2017 - Elsevier
Intestinal homeostasis is maintained through the interplay of the intestinal mucosa, local and systemic immune factors, and the microbial content of the gut. The cellular processes of …
MI Cheng, C Chen, P Engström, DA Portnoy… - Cellular …, 2018 - Wiley Online Library
Listeria monocytogenes grows in the host cytosol and uses the surface protein ActA to promote actin polymerisation and mediate actin‐based motility. ActA, along with two …