Lighting up micro-/nanorobots with fluorescence

M Yang, X Guo, F Mou, J Guan - Chemical Reviews, 2022 - ACS Publications
Micro-/nanorobots (MNRs) can be autonomously propelled on demand in complex
biological environments and thus may bring revolutionary changes to biomedicines …

the role and mechanisms of macrophage autophagy in sepsis

P Qiu, Y Liu, J Zhang - Inflammation, 2019 - Springer
Sepsis is a systemic inflammatory response syndrome caused by infection. The core
mechanism underlying sepsis is immune dysfunction, with macrophages, as important cells …

Regulation of autophagy by the Rab GTPase network

X Ao, L Zou, Y Wu - Cell Death & Differentiation, 2014 - nature.com
Autophagy (macroautophagy) is a highly conserved intracellular and lysosome-dependent
degradation process in which autophagic substrates are enclosed and degraded by a …

Macrophage polarization in response to epigenetic modifiers during infection and inflammation

U Patel, S Rajasingh, S Samanta, T Cao, B Dawn… - Drug discovery today, 2017 - Elsevier
Highlights•This review is focusing on polarization of macrophages by epigenetic
modifications.•M1/M2 macrophages are flawlessly synchronized, specialized, and perform …

Bacterial programmed cell death induced by nanotherapeutic strategies

Y Hu, J Shao, H Dong, D Yang, X Dong - ACS Materials Letters, 2024 - ACS Publications
Programmed cell death (PCD) is crucial for cell renewal, embryogenesis, the immune
response, tissue growth regulation, and other essential biological processes. Recent …

Mycobacterium tuberculosis LprE suppresses TLR2-dependent cathelicidin and autophagy expression to enhance bacterial survival in macrophages

A Padhi, K Pattnaik, M Biswas, M Jagadeb… - The Journal of …, 2019 - journals.aai.org
Despite representing a very important class of virulence proteins, the role of lipoproteins in
the pathogenesis of Mycobacterium tuberculosis remains elusive. In this study, we …

The role of autophagy in colitis-associated colorectal cancer

Y Wu, J Yao, J Xie, Z Liu, Y Zhou, H Pan… - Signal transduction and …, 2018 - nature.com
Autophagy is an evolutionarily conserved catabolic process that eliminates harmful
components through lysosomal degradation. In addition to its role in maintaining cellular …

Autophagy in macrophages: impacting inflammation and bacterial infection

A Vural, JH Kehrl - Scientifica, 2014 - Wiley Online Library
Macrophages are on the front line of host defense. They possess an array of germline‐
encoded pattern recognition receptors/sensors (PRRs) that recognize pathogen‐associated …

The role of barrier function, autophagy, and cytokines in maintaining intestinal homeostasis

D Elshaer, J Begun - Seminars in cell & developmental biology, 2017 - Elsevier
Intestinal homeostasis is maintained through the interplay of the intestinal mucosa, local and
systemic immune factors, and the microbial content of the gut. The cellular processes of …

Actin‐based motility allows Listeria monocytogenes to avoid autophagy in the macrophage cytosol

MI Cheng, C Chen, P Engström, DA Portnoy… - Cellular …, 2018 - Wiley Online Library
Listeria monocytogenes grows in the host cytosol and uses the surface protein ActA to
promote actin polymerisation and mediate actin‐based motility. ActA, along with two …