Epidemiology of myelodysplastic syndromes: why characterizing the beast is a prerequisite to taming it

AM Zeidan, RM Shallis, R Wang, A Davidoff, X Ma - Blood reviews, 2019 - Elsevier
Myelodysplastic syndromes (MDS) consist of a heterogeneous group of myeloid neoplasms
characterized by inefficient hematopoiesis, variable cytopenias and a considerable risk of …

Acute myeloid leukemia and myelodysplastic syndromes in older adults

HD Klepin, AV Rao, TS Pardee - Journal of clinical oncology, 2014 - ascopubs.org
Treatment of older adults with acute myeloid leukemia (AML) or myelodysplastic syndromes
(MDS) is challenging because of disease morbidity and associated treatments. Both …

Clinical outcomes of older patients with AML receiving hypomethylating agents: a large population-based study in the United States

AM Zeidan, R Wang, X Wang, RM Shallis… - Blood …, 2020 - ashpublications.org
The hypomethylating agents (HMAs) azacitidine and decitabine have been the de facto
standard of care for patients with acute myeloid leukemia (AML) who are unfit for intensive …

Transfusion dependence, use of hospice services, and quality of end-of-life care in leukemia

TW LeBlanc, PC Egan… - Blood, The Journal of the …, 2018 - ashpublications.org
Hospice provides high-quality end-of-life care, but patients with leukemias use hospice
services less frequently than those with solid tumors. Transfusion dependence (TD) may …

Comparative clinical effectiveness of azacitidine versus decitabine in older patients with myelodysplastic syndromes

AM Zeidan, AJ Davidoff, JB Long, X Hu… - British journal of …, 2016 - Wiley Online Library
The hypomethylating agents (HMA s) azacitidine and decitabine are both approved for
treatment of myelodysplastic syndromes (MDS) in the USA. In Europe, decitabine is not …

Comparison of risk stratification tools in predicting outcomes of patients with higher-risk myelodysplastic syndromes treated with azanucleosides

AM Zeidan, MA Sekeres, G Garcia-Manero… - Leukemia, 2016 - nature.com
Established prognostic tools in patients with myelodysplastic syndromes (MDS) were largely
derived from untreated patient cohorts. Although azanucleosides are standard therapies for …

Lenalidomide use in myelodysplastic syndromes: Insights into the biologic mechanisms and clinical applications

M Stahl, AM Zeidan - Cancer, 2017 - Wiley Online Library
Myelosysplastic syndromes (MDS) include a heterogeneous group of clonal myeloid
neoplasms characterized by ineffective hematopoiesis leading to blood cytopenias and a …

Therapeutic strategies in low and high-risk MDS: What does the future have to offer?

E Scalzulli, S Pepe, G Colafigli, M Breccia - Blood Reviews, 2021 - Elsevier
Myelodysplastic syndromes (MDS) are a heterogeneous group of myeloid disorders
characterized by cytopenias and increased risk of acute leukemia transformation. Prognosis …

Deferasirox therapy is associated with reduced mortality risk in a medicare population with myelodysplastic syndromes

AM Zeidan, F Hendrick, E Friedmann… - Journal of …, 2015 - becarispublishing.com
Aims: Iron overload adversely affects patients with myelodysplastic syndromes (MDS), but
benefits of iron chelation therapy have not been clearly demonstrated. We examined the …

Beyond hypomethylating agents failure in patients with myelodysplastic syndromes

AM Zeidan, MA Kharfan-Dabaja… - Current opinion in …, 2014 - journals.lww.com
Beyond hypomethylating agents failure in patients with myelo... : Current Opinion in
Hematology Beyond hypomethylating agents failure in patients with myelodysplastic …