[HTML][HTML] DNA methylation cancer biomarkers: translation to the clinic

WJ Locke, D Guanzon, C Ma, YJ Liew… - Frontiers in …, 2019 - frontiersin.org
Carcinogenesis is accompanied by widespread DNA methylation changes within the cell.
These changes are characterized by a globally hypomethylated genome with focal …

Liquid biopsy in bladder cancer: State of the art and future perspectives

F Crocetto, B Barone, M Ferro, GM Busetto… - Critical Reviews in …, 2022 - Elsevier
Bladder cancer is the most common malignancy of the urinary tract. Cystoscopy represents
the gold standard in the diagnosis of suspicious bladder lesions. However, the procedure is …

[HTML][HTML] DNA methylation as a noninvasive epigenetic biomarker for the detection of cancer

C Leygo, M Williams, HC Jin, MWY Chan, WK Chu… - Disease …, 2017 - hindawi.com
In light of the high incidence and mortality rates of cancer, early and accurate diagnosis is an
important priority for assigning optimal treatment for each individual with suspected illness …

[HTML][HTML] Methylation biomarkers for early cancer detection and diagnosis: Current and future perspectives

J Ibrahim, M Peeters, G Van Camp… - European Journal of …, 2023 - Elsevier
The increase in recent scientific studies on cancer biomarkers has brought great new
insights into the field. Moreover, novel technological breakthroughs such as long read …

Liquid biopsy biomarkers in bladder cancer: a current need for patient diagnosis and monitoring

I Lodewijk, M Dueñas, C Rubio… - International journal of …, 2018 - mdpi.com
Bladder Cancer (BC) represents a clinical and social challenge due to its high incidence
and recurrence rates, as well as the limited advances in effective disease management …

[HTML][HTML] Advances in diagnosis and therapy for bladder cancer

X Hu, G Li, S Wu - Cancers, 2022 - mdpi.com
Simple Summary The clinical management of bladder cancer has been developing in the
past decade, including diagnostic tools and treatment options. Both monotherapy and …

DNA methylation as a therapeutic target for bladder cancer

SP Nunes, R Henrique, C Jerónimo, JM Paramio - Cells, 2020 - mdpi.com
Bladder cancer (BC) is the tenth most frequent cancer worldwide and is associated with high
mortality when diagnosed in its most aggressive form, which is not reverted by the current …

Novel urinary biomarkers for the detection of bladder cancer: a systematic review

WS Tan, WP Tan, MY Tan, P Khetrapal, L Dong… - Cancer treatment …, 2018 - Elsevier
Background Urinary biomarkers for the diagnosis of bladder cancer represents an area of
considerable research which has been tested in both patients presenting with haematuria …

Multiplex assays of bladder cancer protein markers with magnetic structural color hydrogel microcarriers based on microfluidics

X Wei, F Bian, H Zhang, H Wang, Y Zhu - Sensors and Actuators B …, 2021 - Elsevier
Bladder cancer is one of the most common malignant tumors of the urinary system with a
significantly increased incidence in recent years. Tumor biomarkers detection with high …

Non‐invasive diagnosis and surveillance of bladder cancer with driver and passenger DNA methylation in a prospective cohort study

Y Xiao, L Ju, K Qian, W Jin, G Wang… - Clinical and …, 2022 - Wiley Online Library
Background State‐of‐art non‐invasive diagnosis processes for bladder cancer (BLCA)
harbour shortcomings such as low sensitivity and specificity, unable to distinguish between …