Neuroimmunology, albeit a relatively established discipline, has recently sparked numerous
exciting findings on microglia, the resident macrophages of the central nervous system …

Inflammation is an integral part of the body's physiological repair mechanism, unless it
remains unresolved and becomes pathological, as evident in the progressive nature of …

Background Although macrophages (MΦ) are known as essential players in wound healing,
their contribution to recovery from spinal cord injury (SCI) is a subject of debate. The …

Neurogenesis is known to take place in the adult brain. This work identifies T lymphocytes
and microglia as being important to the maintenance of hippocampal neurogenesis and …

Traumatic injury to the central nervous system results in the disruption of the blood
brain/spinal barrier, followed by the invasion of cells and other components of the immune …

Despite wide genetic, environmental and clinical heterogeneity in amyotrophic lateral
sclerosis, a rapidly fatal neurodegenerative disease targeting motoneurons …

For decades, several axioms have prevailed with respect to the relationships between the
CNS and circulating immune cells. Specifically, immune cell entry was largely considered to …

Traumatic brain injury (TBI) is the leading cause of death and disability in young adults in the
developed world. The accuracy of early outcome-prediction remains poor even when all …

Interactions between the central nervous system and the immune system have been studied
primarily in the context of pathology, popularizing the view that interplay between these two …

Progressive loss of dopaminergic neurons in the substantia nigra pars compacta and their
terminal connections in the striatum are central features in Parkinson's disease (PD) …