Background Enrolment is one of the most challenging aspects of conducting clinical trials,
preceded by the process of informed consent (IC). Different strategies to improve recruitment …

Clinical trial enrollment provides various benefits to study participants including early access
to novel therapies that may potentially alter the trajectory of disease states. Trial sponsors …

Background The mismatch between the limited availability versus the high demand of
participants who are in the pre-dementia phase of Alzheimer's disease (AD) is a bottleneck …

Abstract Background Randomized controlled trials (RCTs) are the gold standard to establish
evidence for surgical practice but can be hindered by high costs, complexity, and time …

Background Older patients with multimorbidity are under-represented in experimental
research. Objective To explore the barriers and facilitators to general practitioner (GP) and …

Background: Yoga-based interventions can be effective in preventing type 2 diabetes
mellitus (T2DM). We developed a Yoga program for T2DM prevention (YOGA-DP) among …

Background To improve the site selection process for clinical trials, we expanded a site
survey to include standardized assessments of site commitment time, team experience …

Purpose This study aimed to explore the potential impact of the COVID-19 pandemic on the
health-related quality of life (HRQoL) of humanitarian and healthcare workers and its related …

Background Care transitions from hospital to home are a critical period for patients and their
families, especially after a stroke. The aim of this study was to assess the feasibility, fidelity …

Background: Total sleep deprivation (TSD) combined with bright light therapy (BLT) has
been suggested as a valuable add-on to standard treatment for rapid relief of depression …