Growth factors are critical molecules for tissue repair and regeneration. Therefore,
recombinant growth factors have raised a lot of hope for regenerative medicine applications …

Enzymes generated by natural recruitment and protein engineering have greatly contribute
in various sets of applications. However, their insufficient stability is a bottleneck that limit the …

A grand challenge in the field of structural biology is to design and engineer proteins that
exhibit targeted functions. Although much success on this front has been achieved, design …

Gold nanoparticles (AuNPs) have undergone significant research for their use in the
treatment of cancer. Numerous researchers have established their potent antitumor …

Proteins rely on flexibility to respond to environmental changes, ligand binding and chemical
modifications. Potentially, a perturbation that changes the flexibility of a protein may interfere …

The use of enzymes for industrial and biomedical applications is limited to their function at
elevated temperatures. The principles of thermostability engineering need to be …

Glycosaminoglycans (GAGs) are long, linear polysaccharides comprised of repeating
disaccharide units with pleiotropic biological functions, with the non-sulfated GAG hyaluronic …

Fibroblast growth factor (FGF), transforming growth factor (TGF)/Nodal, and Insulin/insulin-
like growth factor (IGF) signaling pathways are sufficient to maintain human embryonic stem …

Despite their name, fibroblast growth factors (FGFs) are multifunctional regulators affecting a
wide variety of physiological events. This review summarizes our recent studies on FGFs …

Cell surface hemichannels (HCs) composed of different connexin (Cx) types are present in
diverse cells and their possible role on FGF-1–induced cellular responses remains …