Non-coding RNAs regulating mitochondrial function in cardiovascular diseases

X Ao, W Ding, X Li, Q Xu, X Chen, X Zhou… - Journal of Molecular …, 2023 - Springer
Cardiovascular disease (CVD) is the leading cause of disease-related death worldwide and
a significant obstacle to improving patients' health and lives. Mitochondria are core …

miRNA dysregulation in cardiovascular diseases: current opinion and future perspectives

F Sessa, M Salerno, M Esposito, G Cocimano… - International Journal of …, 2023 - mdpi.com
MicroRNAs (miRNAs), small noncoding RNAs, are post-transcriptional gene regulators that
can promote the degradation or decay of coding mRNAs, regulating protein synthesis. Many …

A systematic review of miRNAs as biomarkers for chemotherapy-induced cardiotoxicity in breast cancer patients reveals potentially clinically informative panels as well …

C Brown, M Mantzaris, E Nicolaou, G Karanasiou… - Cardio-Oncology, 2022 - Springer
Breast cancer patients are at a particularly high risk of cardiotoxicity from chemotherapy
having a detrimental effect on quality-of-life parameters and increasing the risk of mortality …

Detection of myocardial fibrosis: where we stand

L Zhu, Y Wang, S Zhao, M Lu - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Myocardial fibrosis, resulting from the disturbance of extracellular matrix homeostasis in
response to different insults, is a common and important pathological remodeling process …

MicroRNAs in hypertrophic cardiomyopathy: pathogenesis, diagnosis, treatment potential and roles as clinical biomarkers

F Luo, W Liu, H Bu - Heart Failure Reviews, 2022 - Springer
Hypertrophic cardiomyopathy (HCM) is the most common heritable cardiomyopathy and is
characterized by increased left ventricular wall thickness, but existing diagnostic and …

New insights into the functions of MicroRNAs in cardiac fibrosis: from mechanisms to therapeutic strategies

Y Zhao, D Du, S Chen, Z Chen, J Zhao - Genes, 2022 - mdpi.com
Cardiac fibrosis is a significant global health problem associated with almost all types of
heart disease. Extensive cardiac fibrosis reduces tissue compliance and contributes to …

Circulating miR-499a-5p Is a Potential Biomarker of MYH7—Associated Hypertrophic Cardiomyopathy

N Baulina, M Pisklova, I Kiselev, O Chumakova… - International Journal of …, 2022 - mdpi.com
Hypertrophic cardiomyopathy (HCM) is the most common inherited myocardial disease with
significant genetic and phenotypic heterogeneity. To search for novel biomarkers, which …

[HTML][HTML] Small extracellular vesicles associated miRNA in myocardial fibrosis

M Long, M Cheng - Biochemical and Biophysical Research …, 2024 - Elsevier
Myocardial fibrosis involves the loss of cardiomyocytes, myocardial fibroblast proliferation,
and a reduction in angiogenesis, ultimately leading to heart failure, Given its significant …

Biological Implications of MicroRNAs as Regulators and Biomarkers of Therapeutic Toxicities in Breast Cancer

R Abbas Syed, MG Davey, V Richard, N Miller… - International Journal of …, 2023 - mdpi.com
Contemporary breast cancer management includes surgical resection combined with a
multimodal approach, including chemotherapy, radiotherapy, endocrine therapy, and …

[HTML][HTML] Pulmonary Fibrosis and Diabetes Mellitus: Two coins with the same face

YM Mari, MP Fraix, DK Agrawal - Archives of internal medicine …, 2024 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) constitutes a long-term disease with a complex
pathophysiology composed of multiple molecular actors that lead to the deposition of …