[HTML][HTML] A weight of evidence review of the genotoxicity of titanium dioxide (TiO2)

D Kirkland, MJ Aardema, RV Battersby… - Regulatory Toxicology …, 2022 - Elsevier
Titanium dioxide is a ubiquitous white material found in a diverse range of products from
foods to sunscreens, as a pigment and thickener, amongst other uses. Titanium dioxide has …

Understanding the role of biomolecular coronas in human exposure to nanomaterials

MG Soliman, A Martinez-Serra, G Antonello… - Environmental …, 2024 - pubs.rsc.org
Nanomaterials (NMs) are increasingly used in medical treatments, electronics, and food
additives. However, nanosafety—the possible adverse effects of NMs on human health—is …

Impact of food matrices on the characteristics and cellular toxicities of ingested nanoplastics in a simulated digestive tract

Z Li, Y Huang, Y Zhong, B Liang, X Yang… - Food and Chemical …, 2023 - Elsevier
Microplastic and nanoplastic (MNP) pollution has become a major global food safety
concern. MNPs can interact with food matrices, and their passage through the …

Data-driven quantitative intrinsic hazard criteria for nanoproduct development in a safe-by-design paradigm: a case study of silver nanoforms

I Furxhi, R Bengalli, G Motta, P Mantecca… - ACS Applied Nano …, 2023 - ACS Publications
The current European (EU) policies, that is, the Green Deal, envisage safe and sustainable
practices for chemicals, which include nanoforms (NFs), at the earliest stages of innovation …

Interactions between nanoparticles and intestine

M Vitulo, E Gnodi, R Meneveri, D Barisani - International Journal of …, 2022 - mdpi.com
The use of nanoparticles (NPs) has surely grown in recent years due to their versatility, with
a spectrum of applications that range from nanomedicine to the food industry. Recent …

[HTML][HTML] Investigating the ROS Formation and Particle Behavior of Food-Grade Titanium Dioxide (E171) in the TIM-1 Dynamic Gastrointestinal Digestion Model

NS Bischoff, AK Undas, G van Bemmel, JJ Briedé… - Nanomaterials, 2024 - mdpi.com
Food-grade titanium dioxide (E171) is widely used in food, feed, and pharmaceuticals for its
opacifying and coloring properties. This study investigates the formation of reactive oxygen …

[HTML][HTML] A review of research on the impact of E171/TiO2 NPs on the digestive tract

E Baranowska-Wójcik, D Szwajgier… - Journal of Trace …, 2022 - Elsevier
Nanotechnology utilises particles of between 1 and 100 nm in size. In recent years, it has
enjoyed widespread application in a variety of areas. However, this has also raised …

Changes of physico-chemical properties of nano-biomaterials by digestion fluids affect the physiological properties of epithelial intestinal cells and barrier models

G Antonello, A Marucco, E Gazzano… - Particle and Fibre …, 2022 - Springer
Background The widespread use of nano-biomaterials (NBMs) has increased the chance of
human exposure. Although ingestion is one of the major routes of exposure to NBMs, it is not …

[HTML][HTML] Bioconjugation of Serratiopeptidase with Titanium Oxide Nanoparticles: Improving Stability and Antibacterial Properties

JJ Melchor-Moncada, S Vasquez-Giraldo… - Journal of Functional …, 2024 - mdpi.com
Antimicrobial resistance (AMR) poses a significant global health threat, necessitating the
development of novel antibacterial strategies. Serratiopeptidase (SP), a metalloprotease …

Elucidating the Size‐Dependency of In Vitro Digested Polystyrene Microplastics on Human Intestinal Cells Health and Function

Y Ma, JYC Koh, HK Lim, P Shi… - … Chemistry and Physics, 2022 - Wiley Online Library
The prevalence of microplastics (MPs) contamination in a broad spectrum of potable water
sources has raised significant environmental and public health concerns. While evidence of …