Ophthalmic Aspects of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Narrative Review

G Tóth, A Lukács, F Schirra, GL Sándor, P Killik… - Ophthalmology and …, 2023 - Springer
The aim of our review article was to summarize the current literature on Stevens–Johnson
syndrome (SJS) and its severe form, toxic epidermal necrolysis (TEN). SJS/TEN is a serious …

Allopurinol: Clinical Considerations in the Development and Treatment of Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis, and Other Associated Drug …

KM Dillman, AM Hawkins, AR Ragland, GC Wester… - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Allopurinol lowers urate production through the inhibition of xanthine oxidase. It is
oxidatively hydroxylated to oxypurinol and is the most prescribed medication for gout …

Correlations between histopathologic findings, serum biomarker levels, and clinical outcomes in Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN)

D Chuenwipasakul, C Washrawirul, R Panpruk… - Scientific Reports, 2023 - nature.com
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe
dermatological emergencies. The role of cytokines and chemokines in the pathogenesis …

Stevens-Johnson syndrome and toxic epidermal necrolysis: 11-year retrospective experience in a high-complexity tertiary hospital in Milan, Italy

JW Schroeder, V Caputo, S Guida, F Conte… - Clinics in …, 2023 - Elsevier
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe drug-
induced hypersensitivity reactions characterized by widespread epidermal necrosis, mucous …

APOA4 as a novel predictor of prognosis in Stevens-Johnson syndrome/toxic epidermal necrolysis: a proteomics analysis from two prospective cohorts

T Gong, P Zhang, SF Ruan, Z Xiao, W Chen… - Journal of the American …, 2023 - Elsevier
Background Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are
rare but life-threatening adverse drug reactions. Conventional systemic therapies are of …

Upregulation of IL-37 in epithelial cells: A potential new mechanism of T cell inhibition induced by tacrolimus

Z Su, J Lu, Z Ling, W Li, X Yang, B Cheng… - Biochemical …, 2023 - Elsevier
Oral lichen planus (OLP) is a chronic T cell-mediated mucocutaneous disease characterized
by T cell infiltration at the connective tissue–epithelium interface. Traditionally, topical …

[HTML][HTML] Immunological Mechanisms in Cutaneous Adverse Drug Reactions

AY Lee - Biomolecules & Therapeutics, 2024 - ncbi.nlm.nih.gov
Adverse drug reactions (ADRs) are an inherent aspect of drug use. While approximately
80% of ADRs are predictable, immune system-mediated ADRs, often unpredictable, are a …

High risk and low prevalence diseases: Stevens Johnson syndrome and toxic epidermal necrolysis

C van Nispen, B Long, A Koyfman - The American Journal of Emergency …, 2024 - Elsevier
Abstract Introduction Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis
(TEN) are serious conditions that carry a high rate of morbidity and mortality. Objective This …

Toxic epidermal necrolysis caused by phenobarbital: a case report and literature review

J Cheng, H Li, Y Li, X Li, J Wang, X Huang… - Frontiers in …, 2024 - frontiersin.org
Background Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are
rare, life-threatening immunologic reactions. Previous relevant literature has provided …

Diffuse rash followed by erosions on the lips and mouth

P Larrieu-Jimenez, J Gonzalez, N Crenshaw… - The Journal for Nurse …, 2023 - Elsevier
This is the case of a patient who presented with a chief complaint of mouth pain and a
nonpruritic rash over her arms and hands bilaterally as a diagnostic challenge. The …