Oxidative stress occurs through an imbalance between the generation of reactive oxygen
species (ROS) and the antioxidant defense mechanisms of cells. The eye is particularly …

Many retinal diseases, such as diabetic retinopathy, glaucoma, and age-related macular
(AMD) degeneration, are associated with elevated reactive oxygen species (ROS) levels …

Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of
retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve. The etiology …

The human eye, the highly specialized organ of vision, is greatly influenced by oxidants of
endogenous and exogenous origin. Oxidative stress affects all structures of the human eye …

Glaucoma is a neurodegenerative disease of the visual system and leading cause of
blindness worldwide. The disease is associated with sensitivity to intraocular pressure (IOP) …

Glaucoma is a leading cause of irreversible blindness worldwide. While intraocular pressure
(IOP) presents a major risk factor, the underlying pathophysiology still remains largely …

Most irreversible blindness observed with glaucoma and retina-related ocular diseases,
including age-related macular degeneration and diabetic retinopathy, have their origin in the …

Glaucoma is characterised by loss of retinal ganglion cells, and their axons and many
pathophysiological processes are postulated to be involved. It is increasingly understood …

Angiotensin II (Ang II) has been implicated in the pathophysiology of various age-dependent
ocular diseases. The purpose of this study was to test the hypothesis that Ang II induces …

Glaucoma, a group of diseases characterized by progressive retinal ganglion cell loss,
cupping of the optic disc, and a typical pattern of visual field defects, is a leading cause of …