[HTML][HTML] Bioactive compounds in oxidative stress-mediated diseases: targeting the NRF2/ARE signaling pathway and epigenetic regulation

M Thiruvengadam, B Venkidasamy, U Subramanian… - Antioxidants, 2021 - mdpi.com
Oxidative stress is a pathological condition occurring due to an imbalance between the
oxidants and antioxidant defense systems in the body. Nuclear factor E2-related factor 2 …

[HTML][HTML] Anthocyanins: Promising natural products with diverse pharmacological activities

J Liu, H Zhou, L Song, Z Yang, M Qiu, J Wang, S Shi - Molecules, 2021 - mdpi.com
Anthocyanins are natural products that give color to plants. As natural plant pigments,
anthocyanins also have a series of health-promoting benefits. Many researchers have …

[HTML][HTML] The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions

A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …

[HTML][HTML] Comprehensive overview of Nrf2-related epigenetic regulations involved in ischemia-reperfusion injury

J Zhang, W Pan, Y Zhang, M Tan, Y Yin, Y Li… - Theranostics, 2022 - ncbi.nlm.nih.gov
Ischemic disease is a class of diseases in which an organ is ischemic due to vascular
occlusion, a major contributor to death and disability worldwide. However, when the blood …

[HTML][HTML] The potential of flavonoids and flavonoid metabolites in the treatment of neurodegenerative pathology in disorders of cognitive decline

J Melrose - Antioxidants, 2023 - mdpi.com
Flavonoids are a biodiverse family of dietary compounds that have antioxidant, anti-
inflammatory, antiviral, and antibacterial cell protective profiles. They have received …

[HTML][HTML] Epigenetic regulation of NRF2/KEAP1 by phytochemicals

S Bhattacharjee, RH Dashwood - Antioxidants, 2020 - mdpi.com
Epigenetics has provided a new dimension to our understanding of nuclear factor erythroid
2–related factor 2/Kelch-like ECH-associated protein 1 (human NRF2/KEAP1 and murine …

[HTML][HTML] Bioactive compounds from by-products of eggplant: Functional properties, potential applications and advances in valorization methods

A Karimi, M Kazemi, SA Samani… - Trends in Food Science & …, 2021 - Elsevier
Background Eggplant (also known as aubergine) by-products, which consist mostly of peel
and calyx, are generated in substantial amounts by industrial food processing sections and …

[HTML][HTML] Chemistry and pharmacological actions of delphinidin, a dietary purple pigment in anthocyanidin and anthocyanin forms

A Husain, H Chanana, SA Khan… - Frontiers in …, 2022 - frontiersin.org
Anthocyanins are naturally occurring water-soluble flavonoids abundantly present in fruits
and vegetables. They are polymethoxyderivatives of 2-phenyl-benzopyrylium or flavylium …

[HTML][HTML] Novel insights into prebiotic properties on human health: A review

IA Neri-Numa, GM Pastore - Food Research International, 2020 - Elsevier
Dietary prebiotics can be metabolized by different colonic microorganisms and release
several classes of metabolites, particularly SCFAs into the intestine lumen, influencing the …

[HTML][HTML] Natural bioactive compounds targeting histone deacetylases in human cancers: recent updates

A Bouyahya, N El Hachlafi, T Aanniz, I Bourais… - Molecules, 2022 - mdpi.com
Cancer is a complex pathology that causes a large number of deaths worldwide. Several
risk factors are involved in tumor transformation, including epigenetic factors. These factors …