Millions of patients worldwide have benefited from technological innovation from
biomaterials. Yet, while life expectancy continues to increase, organ failure and traumatic …

Bone grafts have traditionally come from four sources: the patients' own tissue (autograft),
tissue from a living or cadaveric human donor (allograft), animal donors (xenograft) and …

MicroRNAs (miRNAs) are being developed to enhance tissue regeneration. Here we show
that a hyperbranched polymer with high miRNA-binding affinity and negligible cytotoxicity …

Purpose of this study was the analysis of the role of density and pore interconnection
pathway in scaffolds to be used as bone substitutes. We have considered 2 hydroxyapatite …

Magnetite/gold (Fe3O4/Au) hybrid nanoparticles were synthesized from a single iron
precursor (ferric chloride) through a green chemistry route using grape seed …

Recent studies suggest that human adipose tissue contains pluripotent stem cells, which are
similar to bone marrow-derived stem cells. The objective of the present study was to assess …

We describe a novel bioreactor system for tissue engineering of bone that enables
cultivation of up to six tissue constructs simultaneously, with direct perfusion and imaging …

Osteocytes are terminally differentiated bone cells, derived from osteoblasts, which are vital
for the regulation of bone formation and resorption. ECM stiffness and cell seeding density …

Tissue engineering combines principles of the life sciences and engineering to replace and
repair damaged human tissue. Present tissue engineering methods generally require the …

In this study, we evaluated the role of fiber size scale in the adhesion and spreading
potential of human mesenchymal stem cells (hMSCs) on electrospun poly …