Application of nanotechnology in the treatment of glomerulonephritis: current status and future perspectives

HQ Zhan, X Zhang, XL Chen, L Cheng… - Journal of …, 2024 - Springer
Glomerulonephritis (GN) is the most common cause of end-stage renal failure worldwide; in
most cases, it cannot be cured and can only delay the progression of the disease. At …

[HTML][HTML] Renal intrinsic cells remodeling in diabetic kidney disease and the regulatory effects of SGLT2 Inhibitors

W Guo, H Li, Y Li, W Kong - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Diabetic kidney disease (DKD) is a prevalent complication of diabetes and a major
secondary factor leading to end-stage renal disease. The kidney, a vital organ, is composed …

The role of cellular crosstalk in the progression of diabetic nephropathy

K Zhang, Z Fu, Y Zhang, X Chen, G Cai… - Frontiers in …, 2023 - frontiersin.org
Diabetic nephropathy (DN) is one of the most common complications of diabetes, and its
main manifestations are progressive proteinuria and abnormal renal function, which …

[HTML][HTML] 负载小鼠脂肪干细胞的甲壳素/透明质酸/胶原水凝胶的制备及其对大鼠全层皮肤缺损创面愈合的作用

刘颖, 程凤, 王泽薇, 金红旭, 曹滨验… - 中华烧伤与创面 …, 2024 - zhsszz.xml-journal.net
目的制备负载小鼠脂肪干细胞的甲壳素/透明质酸/胶原水凝胶并探讨其对大鼠全层皮肤缺损创面
愈合的作用. 方法该研究为实验研究. 通过酸水解碱的方法提取甲壳素纳米纤维 …

Sublytic C5b-9 induces TIMP3 expression by glomerular mesangial cells via TRAF6-dependent KLF5 K63-linked ubiquitination in rat Thy-1 nephritis

S Ying, L Liu, C Luo, Y Liu, C Zhao, W Ge, N Wu… - International …, 2023 - Elsevier
Abstract Rat Thy-1 nephritis (Thy-1N) is an experimental model for studying human
mesangioproliferative glomerulonephritis (MsPGN), and its pathological features are …

The effect of Chinese traditional medicine Huaiqihuang (HQH) on the protection of nephropathy

X Zhang, Y Cheng, Q Zhou, H Huang… - Oxidative medicine …, 2020 - Wiley Online Library
Kidney disease is one of the common diseases with high morbidity and high mortality, which
brings a huge burden to the society and the patient's family. The pathogenesis, treatment …

Ameliorating role of microRNA-378 carried by umbilical cord mesenchymal stem cells-released extracellular vesicles in mesangial proliferative glomerulonephritis

W Chen, F Zhang, X Hou, H Xu, D Tang - Cell Communication and …, 2022 - Springer
Abstract Background Mesenchymal stem cells (MSCs) and their released extracellular
vesicles (Evs) have shown protective effects against kidney diseases. This study aims to …

Nanocarrier-based localized and effective treatment of renal disorders: currently employed targeting strategies

S Ullah, S Burki, AB Munir, G Yousaf, M Shafique - Nanomedicine, 2024 - Taylor & Francis
Renal disorders pose a global health threat, with targeted drug-delivery systems emerging
as a promising strategy to enhance therapy safety and efficacy. Recent efforts have …

Machine Learning-Driven Biomarker Discovery for Skeletal Complications in Type 1 Gaucher Disease Patients

JJ Cebolla, P Giraldo, J Gómez… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Type 1 Gaucher disease (GD1) is a rare, autosomal recessive disorder caused by
glucocerebrosidase deficiency. Skeletal manifestations represent one of the most …

Combination therapy with Chitosan/siRNA nanoplexes targeting PDGF‐D and pdgfr‐β reveals anticancer effect in breast cancer

E Şalva, S Özbaş, S Alan, N Özkan… - The journal of gene …, 2023 - Wiley Online Library
Background Platelet derived growth factors (PDGF)‐D and the expression of its receptor
increase in neoplastic progression of cancer. Co‐silencing of growth factor and receptor can …