The brain is vulnerable to excessive oxidative insults because of its abundant lipid content,
high energy requirements, and weak antioxidant capacity. Reactive oxygen species (ROS) …

The world's population aging progression renders age‐related neurodegenerative diseases
to be one of the biggest unsolved problems of modern society. Despite the progress in …

Free radicals are generated in the brain, as well as in other organs, and their production is
proportional to the brain activity. Due to its low antioxidant capacity, the brain is particularly …

Non-alcoholic fatty liver disease (NAFLD) represents the most common form of chronic liver
disease worldwide (about 25% of the general population) and 3–5% of patients develop non …

Vitamin E is a group of isoprenoid chromanols with different biological activities. It comprises
eight oil‐soluble compounds: four tocopherols, namely, α‐, β‐, γ‐, and δ‐tocopherols; and …

Epilepsy is a chronic disease that affects millions of people worldwide. Antiepileptic drugs
(AEDs) are used to control seizures. Even though parts of their mechanisms of action are …

Epilepsy is a central nervous system disorder involving spontaneous and recurring seizures
that affects 50 million individuals globally. Because approximately one-third of patients with …

Oxidative stress has been established as a well-known pathological condition in several
neurovascular diseases. It starts with increased production of highly oxidizing free-radicals …

Methamphetamine (MA) is a extremely addictive psychostimulant drug with a significant
abuse potential. Long-term MA exposure can induce neurotoxic effects through oxidative …

The therapeutic potential of the tocotrienol group stems from its nutraceutical properties as a
dietary supplement. It is largely considered to be safe when consumed at low doses for …