Depressive symptoms, anxiety and cognitive impairment: emerging evidence in multiple sclerosis

M Margoni, P Preziosa, MA Rocca, M Filippi - Translational Psychiatry, 2023 - nature.com
Neuropsychiatric abnormalities may be broadly divided in two categories: disorders of
mood, affect, and behavior and abnormalities affecting cognition. Among these conditions …

Risk factors for and management of cognitive dysfunction in multiple sclerosis

RHB Benedict, R Zivadinov - Nature Reviews Neurology, 2011 - nature.com
Cognitive impairment is common in multiple sclerosis (MS), especially when assessed by
neuropsychological tests that emphasize mental processing speed, episodic memory, and …

Cognitive impairment in multiple sclerosis–a review of current knowledge and recent research

T Grzegorski, J Losy - Reviews in the Neurosciences, 2017 - degruyter.com
Multiple sclerosis (MS) is a chronic, progressive disease of the central nervous system that is
characterised by inflammatory damage to the myelin sheath. Though often neglected …

Multiple sclerosis-related cognitive changes: a review of cross-sectional and longitudinal studies

MP Amato, V Zipoli, E Portaccio - Journal of the neurological sciences, 2006 - Elsevier
Prevalence estimates of cognitive impairment in multiple sclerosis (MS) range from 40% to
65%, depending on the research setting. Cognitive dysfunction virtually encompasses all the …

Gender differences in human brain: a review

ZF Zaidi - The open anatomy journal, 2010 - benthamopen.com
Why do men and women think differently? Why do they behave differently in stressed
situations? Why do women act more emotionally as compared to men? Why do men and …

The importance of studying sex differences in disease: The example of multiple sclerosis

LC Golden, R Voskuhl - Journal of neuroscience research, 2017 - Wiley Online Library
To date, scientific research has often focused on one sex, with assumptions that study of the
other sex would yield similar results. However, many diseases affect males and females …

Sex differences in brain atrophy in multiple sclerosis

RR Voskuhl, K Patel, F Paul, SM Gold, M Scheel… - Biology of sex …, 2020 - Springer
Background Women are more susceptible to multiple sclerosis (MS) than men by a ratio of
approximately 3: 1. However, being male is a risk factor for worse disability progression …

Estrogen receptor beta in astrocytes modulates cognitive function in mid-age female mice

N Itoh, Y Itoh, CE Meyer, TT Suen… - Nature …, 2023 - nature.com
Menopause is associated with cognitive deficits and brain atrophy, but the brain region and
cell-specific mechanisms are not fully understood. Here, we identify a sex hormone by age …

Sex differences in autoimmune disorders of the central nervous system

SM Gold, A Willing, F Leypoldt, F Paul… - Seminars in …, 2019 - Springer
Stronger adaptive immune responses in females can be observed in different mammals,
resulting in better control of infections compared to males. However, this presumably …

The effect of sex on multiple sclerosis risk and disease progression

RR Voskuhl - Multiple Sclerosis Journal, 2020 - journals.sagepub.com
Sex differences in the incidence or severity of disease characterize many autoimmune and
neurodegenerative diseases. Multiple sclerosis is a complex disease with both autoimmune …