Septins are an integral component of the cytoskeleton, assembling into higher-order
oligomers and filamentous polymers that associate with actin filaments, microtubules and …

The enzymatic generation of carbon–halogen bonds is a powerful strategy used by both
nature and synthetic chemists to tune the bioactivity, bioavailability and reactivity of …

To cause rice blast disease, the fungus Magnaporthe oryzae develops a pressurized dome-
shaped cell called an appressorium, which physically ruptures the leaf cuticle to gain entry …

▪ Abstract Completion of the cell cycle requires the temporal and spatial coordination of
chromosome segregation with mitotic spindle disassembly and cytokinesis. In budding …

The establishment of cell polarity is critical for the development of many organisms and for
the function of many cell types. A large number of studies of diverse organisms from yeast to …

Septins are an evolutionarily conserved group of GTP‐binding and filament‐forming
proteins that belong to the large superclass of P‐loop GTPases. While originally discovered …

Eukaryotic cells from neurons and epithelial cells to unicellular fungi frequently rely on
cellular appendages such as axons, dendritic spines, cilia, and buds for their biology. The …

The murine septin4 gene (Sept4) has been implicated in diverse cellular functions, including
cytokinesis, apoptosis, and tumor suppression. Here, we investigated the function of Sept4 …

Septins are conserved GTP-binding proteins that assemble into hetero-oligomeric
complexes and higher-order structures such as filaments, rings, hourglasses or gauzes …

Coordination of cytokinesis with chromosome congression and segregation is critical for
proper cell division, but the mechanism is unknown. Here, septins, a conserved family of …