Green chemistry meets medicinal chemistry: a perspective on modern metal-free late-stage functionalization reactions

JD Lasso, DJ Castillo-Pazos, CJ Li - Chemical Society Reviews, 2021 - pubs.rsc.org
The progress of drug discovery and development is paced by milestones reached in organic
synthesis. In the last decade, the advent of late-stage functionalization (LSF) reactions has …

Functionalizing nanoparticles with biological molecules: developing chemistries that facilitate nanotechnology

KE Sapsford, WR Algar, L Berti, KB Gemmill… - Chemical …, 2013 - ACS Publications
Bionanotechnology has now become firmly established in its own right as one of the
principle and focused subdisciplines within nanotechnology.(1-10) Bionanotechnology can …

Thiyl radicals in organic synthesis

F Denes, M Pichowicz, G Povie, P Renaud - Chemical reviews, 2014 - ACS Publications
Thiyl radicals have been used by nature in a broad range of biochemical processes. For
instance, thiol residues play an important role in many enzymatic processes as illustrated by …

Magnetic nanoadsorbents' potential route for heavy metals removal—a review

FSA Khan, NM Mubarak, M Khalid, R Walvekar… - … Science and Pollution …, 2020 - Springer
Due to the rapid growth in the heavy metal-based industries, their effluent and local dumping
have created significant environmental issues. In the past, typically, removal of heavy metals …

Photoclick chemistry: a bright idea

BD Fairbanks, LJ Macdougall, S Mavila, J Sinha… - Chemical …, 2021 - ACS Publications
At its basic conceptualization, photoclick chemistry embodies a collection of click reactions
that are performed via the application of light. The emergence of this concept has had …

Thiol–ene click chemistry: Computational and kinetic analysis of the influence of alkene functionality

BH Northrop, RN Coffey - Journal of the American Chemical …, 2012 - ACS Publications
The influence of alkene functionality on the energetics and kinetics of radical initiated thiol–
ene click chemistry has been studied computationally at the CBS-QB3 level. Relative …

Thiol− ene reaction: synthetic aspects and mechanistic studies of an anti‐Markovnikov‐selective hydrothiolation of olefins

AK Sinha, D Equbal - Asian Journal of Organic Chemistry, 2019 - Wiley Online Library
In synthetic organic chemistry, the anti‐Markovnikov thiol− ene click (TEC) reaction has
emerged as a powerful and widely used approach to build carbon− sulfur (C− S) bonds …

Visible light photocatalytic thiol–ene reaction: an elegant approach for fast polymer postfunctionalization and step-growth polymerization

J Xu, C Boyer - Macromolecules, 2015 - ACS Publications
An elegant approach for fast polymer postfunctionalization and step-growth polymerization
(via addition reaction) under aerobic condition was developed from visible light …

Recent advances in sulfur-and phosphorous-centered radical reactions for the formation of S–C and P–C bonds

XQ Pan, JP Zou, WB Yi, W Zhang - Tetrahedron, 2015 - Elsevier
Free radicals are important subjects in organic, bioorganic, medicinal, material, and
atmospheric chemistries. Synthetic utilities of free radicals have been well-accomplished in …

Understanding the significant role of SiOSi bonds: organosilicon materials as powerful platforms for bioimaging

Y Zuo, X Liang, J Yin, Z Gou, W Lin - Coordination Chemistry Reviews, 2021 - Elsevier
Fluorescence imaging is one of the most powerful methods for the spatial and temporal
visualization of bio-species in living systems. Various fluorescent materials have obtained …