The human calcium-sensing receptor gene (CASR) has 8 exons, and localizes to
chromosome 3q. Exons 1A and 1B encode alternative 5′-untranslated regions (UTRs) that …

Background The pathogenesis of basal ganglia calcification (BGC) in hypoparathyroidism is
not clear. Its occurrence in hypocalcaemic milieu of hypoparathyroidism is believed to be …

Hypoparathyroidism (HP) is clinically characterized by the presence of hypocalcemia,
usually associated with specific signs and symptoms that depend on how severe and …

Hypocalcemia and hyperphosphatemia are encountered in idiopathic hypoparathyroidism
(IHP) and pseudohypoparathyroidism type Ib (PHP1B). In contrast to PHP1B, which is …

Context: Bone mineral density (BMD) is increased in idiopathic hypoparathyroidism (IH).
Parathyroid hormone (PTH) deficiency, hypocalcemic seizures, and anticonvulsants could …

Context: Data on calcium-sensing receptor autoantibodies (CaSRAbs) in
hypoparathyroidism are variable. Objective: We assessed the prevalence and significance …

Purpose Patients with hypoparathyroidism are at risk of vertebral fractures (VFs) despite
high bone mineral density (BMD). We investigated this paradox by assessing trabecular …

Cataract is a cardinal manifestation of hypoparathyroidism. Although patients with
hypoparathyroidism require cataract surgery at a younger age than individuals without …

Haploinsufficiency of the Gata3 gene, which encodes a zinc-finger transcription factor, is
associated with the disorder hypoparathyroidism, deafness, and renal dysplasia (HDR) …

Context There are concerns about the long-term safety of conventional therapy on renal
health in patients with hypoparathyroidism. Careful audit of these would help comparisons …