According to the new classification, periodontitis is defined as a chronic multifactorial
inflammatory disease associated with dysbiotic biofilms and characterized by progressive …

Background Several vitamins, including C, E, and B12, have been recognized as
antioxidants and have shown hepatoprotective effects against the hepatotoxicity caused by …

Background and objectives: Ascorbic acid, alpha lipoic acid (ALA) and silymarin are well-
known antioxidants that have hepatoprotective effects. This study aims to investigate the …

Therapeutic deep eutectic solvents (THEDSs) are the best exemplification of green
alternative formulations of active pharmaceutical ingredients (APIs) that offer superlative …

Osteoarthritis is one of the leading conditions that promote the consumption of these dietary
supplements. Chondroitin sulfate, glucosamine, and methylsulfonylmethane are among the …

Oral route is presented as the gold standard of drug delivery systems within the
pharmaceutical industry being the most safe, non-invasive and the most economic route of …

Background. Long-term use of chondroprotective agents–chondroitin sulfate (CS) and
glucosamine sulfate (GS) in the treatment of osteoarthritis puts forward increased …

Investigation of acetaminophen (APAP)-induced liver damage recently indicated the
significance of phagocytic NADPH oxidase (NOX)-derived reactive oxygen species (ROS) …

Propranolol (PROP) undergoes extensive first-pass metabolism by the liver resulting in a
relatively low bioavailability (13–23%); thus, multiple oral doses are required to achieve …

Purpose This study is aimed at preparing and testing physicochemical, pharmacokinetic and
levels of toxic metabolites of paracetamol and glucosamine solid dispersions intended for …