Gut microbiome lipid metabolism and its impact on host physiology

EM Brown, J Clardy, RJ Xavier - Cell Host & Microbe, 2023 - cell.com
Metabolites produced by commensal gut microbes impact host health through their
recognition by the immune system and their influence on numerous metabolic pathways …

Advancing human gut microbiota research by considering gut transit time

N Procházková, G Falony, LO Dragsted, TR Licht… - Gut, 2023 - gut.bmj.com
Accumulating evidence indicates that gut transit time is a key factor in shaping the gut
microbiota composition and activity, which are linked to human health. Both population-wide …

[HTML][HTML] Intestinal epithelial cell metabolism at the interface of microbial dysbiosis and tissue injury

E Rath, D Haller - Mucosal immunology, 2022 - Elsevier
The intestinal epithelium represents the most regenerative tissue in the human body, located
in proximity to the dense and functionally diverse microbial milieu of the microbiome …

What defines a healthy gut microbiome?

M Van Hul, PD Cani, C Petitfils, WM De Vos, H Tilg… - Gut, 2024 - gut.bmj.com
The understanding that changes in microbiome composition can influence chronic human
diseases and the efficiency of therapies has driven efforts to develop microbiota-centred …

The roles of dietary lipids and lipidomics in gut-brain axis in type 2 diabetes mellitus

D Ağagündüz, MA Icer, O Yesildemir, T Koçak… - Journal of translational …, 2023 - Springer
Type 2 diabetes mellitus (T2DM), one of the main types of Noncommunicable diseases
(NCDs), is a systemic inflammatory disease characterized by dysfunctional pancreatic β …

Gut microbiota and microbial metabolism in early risk of cardiometabolic disease

CL Gabriel, JF Ferguson - Circulation Research, 2023 - Am Heart Assoc
Cardiometabolic disease comprises cardiovascular and metabolic dysfunction and
underlies the leading causes of morbidity and mortality, both within the United States and …

Gut microbiota bridges the iron homeostasis and host health

L Xiao, R Tang, J Wang, D Wan, Y Yin, L Xie - Science China Life …, 2023 - Springer
The gut microbiota acts as a symbiotic microecosystem that plays an indispensable role in
the regulation of a number of metabolic processes in the host by secreting secondary …

Treatment of dyslipidemia through targeted therapy of gut microbiota

B Flaig, R Garza, B Singh, S Hamamah, M Covasa - Nutrients, 2023 - mdpi.com
Dyslipidemia is a multifaceted condition with various genetic and environmental factors
contributing to its pathogenesis. Further, this condition represents an important risk factor for …

Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease

X Zhou, X Shen, JS Johnson, DJ Spakowicz… - Cell Host & Microbe, 2024 - cell.com
To understand the dynamic interplay between the human microbiome and host during
health and disease, we analyzed the microbial composition, temporal dynamics, and …

Quantitative microbiome profiling reveals the developmental trajectory of the chicken gut microbiota and its connection to host metabolism

Y Feng, M Zhang, Y Liu, X Yang, F Wei, X Jin, D Liu… - Imeta, 2023 - Wiley Online Library
Revealing the assembly and succession of the chicken gut microbiota is critical for a better
understanding of its role in chicken physiology and metabolism. However, few studies have …