With recent advances and commercial implementation of minimally invasive biomarkers in
kidney transplantation, new strategies for the surveillance of allograft health are emerging …

Early diagnosis is critical to minimizing the damage rejection can do to the transplanted
kidney. Donor-derived cell-free DNA (dd-cfDNA) represents non-encapsulated fragmented …

Hematopoietic stem cell transplantation (HSCT) is the only established curative treatment for
sickle cell disease (SCD), a debilitating red blood cell (RBC) disorder with significant …

Heart transplantation (HTx) is considered the gold-standard therapy for the treatment of
advanced heart failure (HF). The long-term survival in HTx is hindered by graft failure which …

Hydroxyurea (HU) is the most common drug therapy for sickle cell disease (SCD). The
clinical benefits of HU derive from its upregulation of fetal hemoglobin (HbF), which reduces …

Post-transplant complications reduce allograft and recipient survival. Current approaches for
detecting allograft injury non-invasively are limited and do not differentiate between cellular …

The process and evolution of an organ transplant procedure has evolved in terms of the
prevention of immunological rejection with the improvement in the determination of immune …