The heat shock response, characterized by increased expression of heat shock proteins
(Hsps) is induced by exposure of cells and tissues to extreme conditions that cause acute or …

This review examines the effects of thermal stress on gene expression, with special
emphasis on changes in the expression of genes other than heat shock proteins (HSPs) …

Emerging evidence revealed the significant roles of heat shock factor 1 (HSF1) in cancer
initiation, development, and progression, but there is no pan‐cancer analysis of HSF1. The …

Heat shock transcription factor (HSF) and the promoter heat shock element (HSE) are
among the most highly conserved transcriptional regulatory elements in nature. HSF …

Molecular oxygen (O2) and carbon dioxide (CO2) are the primary gaseous substrate and
product of oxidative phosphorylation in respiring organisms, respectively. Variance in the …

Fever, a nonspecific acute-phase response, has been associated with improved survival
and shortened disease duration in infections, but the mechanisms of these beneficial …

Sepsis is a highly lethal clinical syndrome characterized by a systemic inflammatory
response to infection. Fever, a non-specific acute-phase response, has been associated …

Objective Life-threatening conditions cause severe changes in the organization and
conformation of macromolecules, creating urgent requirements for protein repair to ensure …

Behavioural fever, defined as an acute change in thermal preference driven by pathogen
recognition, has been reported in a variety of invertebrates and ectothermic vertebrates. It …

The heat shock response is an ancient and highly conserved process that is essential for
surviving environmental stresses, including extremes of temperature. Fever is a more …