Post-traumatic stress disorder (PTSD) is a common, costly, and often debilitating psychiatric
condition. However, the biological mechanisms underlying this disease are still largely …

Considerable individual differences exist in trait-like patterns of behavioral and physiological
responses to salient environmental challenges. This individual variation in stress coping …

Background The limited neurobiological understanding of posttraumatic stress disorder
(PTSD) has been partially attributed to the need for improved animal models. Stress …

Patients with post-traumatic stress disorder have a heightened vulnerability to developing
substance use disorders; however, the biological underpinnings of this vulnerability remain …

Post-traumatic stress disorder (PTSD) is a psychiatric disorder whose pathogenesis relies
on a maladaptive expression of the memory for a life-threatening experience, characterized …

Resilience to consequences of trauma exposure contains relevant information about the
processes that contribute to the maintenance of mental health in the face of adversity; …

Highlights•PTSD and substance use disorders (SUD) present a difficult-to-treat comorbidity.•
Anhedonia stems from deficits in reward functioning and is related to PTSD and SUD.•Few …

Abstract Study Objectives: To examine the REM sleep response to stress and fearful
memories as a potential marker of stress resilience and vulnerability and to assess the role …

The accurate detection and quantification of rodent behavior forms a cornerstone of basic
biomedical research. Current data-driven approaches, which segment free exploratory …

Individuals respond differently to traumatic experiences, including their propensity to
develop posttraumatic stress disorder (PTSD). Understanding individual differences in PTSD …