LOOS (Lightweight Object Oriented Structure‐analysis) is a C++ library designed to facilitate
making novel tools for analyzing molecular dynamics simulations by abstracting out the …

Adrenergic receptors belong to the family of the G protein coupled receptors that represent
important targets in the modern pharmacotherapies. Studies on different physiological and …

Adenosine receptors (ARs) belong to family A of GPCRs that are involved in many diseases,
including cerebral and cardiac ischemic diseases, immune and inflammatory disorders, etc …

G protein-coupled receptors (GPCRs) are known to dimerize, but the molecular and
structural basis of GPCR dimers is not well understood. In this study, we developed a …

The activation/deactivation processes for G‐protein coupled receptors (GPCRs) have been
computationally studied for several different classes, including rhodopsin, the β2 adrenergic …

G protein-coupled receptors are vital membrane proteins that allosterically transduce
biomolecular signals across the cell membrane. However, the process by which ligand …

Os recetores acoplados à proteína G (GPCRs) desempenham funções críticas no
desenvolvimento e progressão de diversas patologias. Muitos membros da família GPCR …

Los factores quimiotácticos y angiogénicos secretados dentro del microambiente tumoral
facilitan la diseminación metastásica de las células cancerosas. El receptor sensor de calcio …

In rational drug design projects one major goal is to obtain high affinity ligands for a target,
while maintaining selectivity over potential off-targets and thereby reducing unwanted side …