Poroma is a benign sweat gland tumour showing morphological features recapitulating the
superficial portion of the eccrine sweat coil. A subset of poromas may transform into …

The term “hemangioendothelioma” is used for endothelial neoplasms of intermediate
malignancy and describes a group of rare neoplasms having biologic behavior falling in …

Giant cell tumors (GCTs) with high mobility group AT-Hook 2 (HMGA2):: nuclear receptor
corepressor 2 (NCOR2) fusion are rare mesenchymal tumors of controversial nosology …

Composite hemangioendothelioma is a rare, locally aggressive, and rarely metastasizing
vascular neoplasm which affects both children and adults. Recently, a number of gene …

Among mesenchymal tumors, MAML2 gene rearrangements have been described in a
subset of composite hemangioendothelioma and myxoinflammatory fibroblastic sarcoma …

Gene fusions are well-known drivers of cancer and are potent targets for molecular therapy.
An emerging spectrum of human tumors harbors recurrent and pathognomonic gene fusions …

Myxoinflammatory fibroblastic sarcoma (MIFS) is an infiltrative, locally aggressive fibroblastic
neoplasm of intermediate malignancy that typically arises in the distal extremities of middle …

Bone and soft tissue tumors (BST) are a highly heterogeneous group largely classified by
their line of differentiation, based on their resemblance to their normal counterpart in adult …

Myxofibrosarcoma is a locally aggressive sarcoma that characteristically arises in the
extremities of older patients. Cases arising at a younger age are rare, leading to diagnostic …

Lipoblastoma-like tumor (LLT) is a benign soft tissue tumor demonstrating mixed
morphologic features of lipoblastoma, myxoid liposarcoma, and spindle cell lipoma but …