Adipose tissue secretion pattern influences β-cell wellness in the transition from obesity to type 2 diabetes

G Biondi, N Marrano, A Borrelli, M Rella… - International Journal of …, 2022 - mdpi.com
The dysregulation of the β-cell functional mass, which is a reduction in the number of β-cells
and their ability to secure adequate insulin secretion, represents a key mechanistic factor …

Plasma adipsin as a biomarker and its implication in type 2 diabetes mellitus

GG Tafere, DZ Wondafrash, KA Zewdie… - Diabetes, Metabolic …, 2020 - Taylor & Francis
Diabetes mellitus (DM) is a worldwide health threat affecting millions of people, which is
associated with different micro-and macro-vascular complications. Type 2 diabetes mellitus …

Adipsin serum concentrations and adipose tissue expression in people with obesity and type 2 diabetes

M Milek, Y Moulla, M Kern, C Stroh, A Dietrich… - International Journal of …, 2022 - mdpi.com
(1) Adipsin is an adipokine that may link increased fat mass and adipose tissue dysfunction
to obesity-related cardiometabolic diseases. Here, we investigated whether adipsin serum …

Association of metabolically healthy and unhealthy obesity phenotype with markers related to obesity, diabetes among young, healthy adult men. Analysis of …

M Lejawa, K Osadnik, Z Czuba, T Osadnik, N Pawlas - Life, 2021 - mdpi.com
Adipose tissue secretes many regulatory factors called adipokines. Adipokines affect the
metabolism of lipids and carbohydrates. They also influence the regulation of the immune …

Effects of adult growth hormone deficiency and replacement therapy on the cardiometabolic risk profile

B Ratku, V Sebestyén, A Erdei, EV Nagy, Z Szabó… - Pituitary, 2022 - Springer
Adult growth hormone deficiency (AGHD) is considered a rare endocrine disorder involving
patients with childhood-onset and adult-onset growth hormone deficiency (AoGHD) and …

Identification of adipsin as a novel prognostic biomarker in patients with coronary artery disease

T Ohtsuki, K Satoh, T Shimizu, S Ikeda… - Journal of the …, 2019 - Am Heart Assoc
Background Circulating proteins are exposed to vascular endothelial layer and influence
their functions. Among them, adipsin is a member of the trypsin family of peptidases and is …

Adipokines, adiposity, and bone marrow adipocytes: Dangerous accomplices in multiple myeloma

EV Morris, CM Edwards - Journal of Cellular Physiology, 2018 - Wiley Online Library
Obesity has become a global epidemic influencing the establishment and progression of a
wide range of diseases, such as diabetes, cardiovascular disease, and cancer. In 2016 …

Serum proteomic identification and validation of two novel atherosclerotic aortic aneurysm biomarkers, profilin 1 and complement factor D

Y Murakami, M Nishigori, H Yagi, T Osaki… - Proteome Science, 2023 - Springer
Background Effective diagnostic biomarkers for aortic aneurysm (AA) that are detectable in
blood tests are required because early detection and rupture risk assessment of AA can …

Relationship between serum adipsin and the first phase of glucose‐stimulated insulin secretion in individuals with different glucose tolerance

Q Zhou, Q Ge, Y Ding, H Qu, H Wei… - Journal of Diabetes …, 2018 - Wiley Online Library
Abstract Aims/Introduction To detect serum adipsin levels in individuals with different
glucose tolerance, and investigate the relationship between adipsisn and the first phase of …

Anthocyanins regulate serum adipsin and visfatin in patients with prediabetes or newly diagnosed diabetes: A randomized controlled trial

L Yang, Y Qiu, W Ling, Z Liu, L Yang, C Wang… - European Journal of …, 2021 - Springer
Background Epidemiological studies have suggested that adipsin and visfatin are
associated with the development of type 2 diabetes. This is the first study to investigate the …