[HTML][HTML] Viperin: An ancient radical SAM enzyme finds its place in modern cellular metabolism and innate immunity

S Ghosh, ENG Marsh - Journal of Biological Chemistry, 2020 - ASBMB
Viperin plays an important and multifaceted role in the innate immune response to viral
infection. Viperin is also notable as one of very few radical SAM–dependent enzymes …

[HTML][HTML] Review on the antiviral organic agents against fish rhabdoviruses

SS Sun, SW Ma, J Li, Q Zhang, GZ Zhou - Fishes, 2023 - mdpi.com
Fish rhabdoviruses are harmful single-stranded RNA viruses with high mortality rates which
cause considerable economic losses in aquaculture. It is imperative to explore and develop …

[HTML][HTML] Identification of Antimicrobial Peptide Genes in Black Rockfish Sebastes schlegelii and Their Responsive Mechanisms to Edwardsiella tarda Infection

M Zhang, M Cao, Y Xiu, Q Fu, N Yang, B Su, C Li - Biology, 2021 - mdpi.com
Simple Summary Sebastes schlegelii is a typical viviparous teleost that belongs to the family
Scorpaenidae, and is an important mariculture fish in East Asian countries such as Japan …

Genome-wide identification and analysis of NOD-like receptors and their potential roles in response to Edwardsiella tarda infection in black rockfish (Sebastes …

M Cao, X Yan, Q Li, Q Fu, N Yang, L Song, C Li - Aquaculture, 2021 - Elsevier
NLR (NOD-like receptor) is a large class of cytoplasmic family protein that belonging to the
pattern recognition receptors (PRRs), which exerts autoimmune activities by detecting …

Generation of viperin-knockout zebrafish by CRISPR/Cas9-mediated genome engineering and the effect of this mutation under VHSV infection

K Shanaka, S Jung, KP Madushani… - Fish & Shellfish …, 2022 - Elsevier
Viperin is an important virus-induced protein in animals that negatively participates in RNA
viral replication and transcription. The reactive machinery of viperin suggests that it …

Galectin 9 restricts viral replication in teleost via autophagy-antiviral pathway and polarizes M2 macrophages for anti-inflammatory response: New insights into …

W Warnakula, HMV Udayantha, DS Liyanage… - Fish & Shellfish …, 2023 - Elsevier
Abstract Galectin 9 (Gal9) is a tandem repeat type ß-galactoside-binding galectin that
mediates various cellular biochemical and immunological functions. Many studies have …

[HTML][HTML] Unexpected regulatory functions of cyprinid Viperin on inflammation and metabolism

L Chaumont, L Jouneau, F Huetz, DR van Muilekom… - BMC genomics, 2024 - Springer
Background Viperin, also known as radical S-adenosyl-methionine domain containing
protein 2 (RSAD2), is an interferon-inducible protein that is involved in the innate immune …

Molecular characterization, expression profile, and antiviral activity of redlip mullet (Liza haematocheila) viperin

KP Madushani, K Shanaka, H Yang, C Lim… - … and Physiology Part B …, 2022 - Elsevier
Viperin is known to exhibit activity against RNA viral infection. Viral hemorrhagic septicemia
virus (VHSV) is a negative-sense single-stranded RNA virus that causes severe loss in …

Characterization and expression analysis of rockfish (Sebastes schlegelii) myeloid differentiation factor-88 (SsMyD88) and evaluation of its ability to induce …

K Shanaka, MDN Tharuka, S Sellaththurai… - Fish & shellfish …, 2020 - Elsevier
Innate immunity is characterized by nonspecific, prompt reactions toward armada of
antigens. Animals funnel down a repertoire of immune stimulants to activate non-selective …

Expression analysis and antiviral activity of koi carp (Cyprinus carpio) viperin against carp edema virus (CEV)

X Wang, R Zhang, L Liu, H Li, H Zhu - Fish & Shellfish Immunology, 2024 - Elsevier
Viperin, also known as radical S-Adenosyl methionine domain containing 2 (RSAD2), is an
IFN stimulated protein that plays crucial roles in innate immunity. Here, we identified a …