Background Methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism was
reported as risk factor for multiple diseases due to its role in conversion of homocysteine to …

Given that foods and nutrients have been shown to influence the pharmacokinetics of drugs,
drugs may cause changes in the nutritional status of patients and their response to a given …

Epilepsy treatment is challenging due to heterogeneous syndromes, different seizure types
and higher inter-individual variability. Identification of genetic variants predicting drug …

Pharmacogenomic studies in epilepsy are necessary due to the high prevalence of this
disease and the high percentage of drug resistance phenotype. Several altered genes …

Background: To determine the influence of phenytoin (PHT) monotherapy on the serum
levels of homocysteine (Hcy), folate and vitamin B12 in patients with epilepsy. Methods …

Objective This article explores current evidence about the effects of valproate (VPA)
medicines on sexual health in men, how to monitor symptoms, communicate with patients …

Objective Long-term therapy with phenytoin and carbamazepine is known to cause
hyperhomocysteinaemia. We evaluated the prevalence of hyperhomocysteinaemia in North …

Epilepsy is a chronic neurological disease of the brain. Over 20 antiseizure medications are
available on the market, but a third of patients still have drug-resistant epilepsy. This study …

Background: Numerous data show a role for genetic polymorphisms in the development of
epilepsy. Previously, the TT genotype of the MTHFR 677C> T polymorphism was found to be …

Background and Objectives: Epilepsy is a chronic brain disease, with inherent and
noninherent factors. Although over 20 anti-seizure medications (ASMs) are commercially …