Flavonoids a bioactive compound from medicinal plants and its therapeutic applications

A Roy, A Khan, I Ahmad, S Alghamdi… - BioMed Research …, 2022 - Wiley Online Library
Plants generally secrete secondary metabolites in response to stress. These secondary
metabolites are very useful for humankind as they possess a wide range of therapeutic …

The SARS‐CoV‐2 main protease (Mpro): Structure, function, and emerging therapies for COVID‐19

Q Hu, Y Xiong, GH Zhu, YN Zhang, YW Zhang… - MedComm, 2022 - Wiley Online Library
The main proteases (Mpro), also termed 3‐chymotrypsin‐like proteases (3CLpro), are a
class of highly conserved cysteine hydrolases in β‐coronaviruses. Increasing evidence has …

Mechanistic action of cell cycle arrest and intrinsic apoptosis via inhibiting Akt/mTOR and activation of p38-MAPK signaling pathways in Hep3B liver cancer cells by …

A Abusaliya, SH Jeong, PB Bhosale, HH Kim, MY Park… - Nutrients, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) has a poor prognosis and a low survival rate. Drugs
without side effects are desperately needed since chemotherapy has a negative effect on …

Strategies for the management of spike protein-related pathology

MTJ Halma, C Plothe, P Marik, TA Lawrie - Microorganisms, 2023 - mdpi.com
In the wake of the COVID-19 crisis, a need has arisen to prevent and treat two related
conditions, COVID-19 vaccine injury and long COVID-19, both of which can trace at least …

Health Effects of Soy Isoflavones and Green Tea Catechins on Cancer and Cardiovascular Diseases Based on Urinary Biomarker Levels

T Ohishi, N Miyoshi, M Mori, M Sagara, Y Yamori - Molecules, 2022 - mdpi.com
Plant polyphenols have various health effects. Genistein, which is abundant in soybeans,
and epigallocatechin-3-gallate, which is abundant in green tea, are major flavonoids, a …

New insights into immunomodulatory properties of lactic acid bacteria fermented herbal medicines

H Zhu, L Guo, D Yu, X Du - Frontiers in Microbiology, 2022 - frontiersin.org
The COVID-19 pandemic has brought more attention to the immune system, the body's
defense against infectious diseases. The immunomodulatory ability of traditional herbal …

Evaluation of the possible pathways involved in the protective effects of quercetin, naringenin, and rutin at the gene, protein and miRNA levels using in-silico …

S Zargar, N Altwaijry, TA Wani, HM Alkahtani - Molecules, 2023 - mdpi.com
Flavonoids are secondary metabolites that are non-essential for plant growth or survival,
and they also provide numerous health benefits to humans. They are antioxidants that shield …

IL-17A regulates autophagy and promotes osteoclast differentiation through the ERK/mTOR/Beclin1 pathway

H Tang, S Zhu, K Chen, S Yuan, J Hu, H Wang - PloS one, 2023 - journals.plos.org
Bone is a frequent target of tumor metastasis, with high incidence rate and poor prognosis.
Osteoclasts play a key role in the process of tumor bone metastasis. Interleukin-17A (IL-17A) …

Bioactive Compounds of Verbascum sinuatum L.: Health Benefits and Potential as New Ingredients for Industrial Applications

P Donn, P Barciela, A Perez-Vazquez, L Cassani… - Biomolecules, 2023 - mdpi.com
Verbascum sinuatum (V. sinuatum) is a plant belonging to the Scrophulariaceae family that
has been used as an ingredient in traditional medicine infusions for the treatment of many …

[HTML][HTML] The Protective Effect of Flavonoids in the Diet on Autophagy-Related Cardiac Impairment

S L'Abbate, C Kusmic - Nutrients, 2024 - mdpi.com
The compounds known as flavonoids, commonly found in fruits, vegetables, legumes,
medicinal herbs, chocolate, and coffee and tea beverages, have been extensively …